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10.1016/j.jinf.2021.05.004 http://scihub22266oqcxt.onion/10.1016/j.jinf.2021.05.004 33992686!8118709!33992686     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33992686&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       J+Infect 2021 ; 83 (1): 1-16 Nephropedia Template TP {{tp|p=33992686|t=2021. Epidemiology and organ specific sequelae of post-acute COVID19: A narrative review |pdf=|usr=}}{{33992686}} gab.com Text Epidemiology and organ specific sequelae of post-acute COVID19: A narrative review JO: J Infect http://www.kidney.de/pget.php?&tw=1&pmid=33992686 #FOAvip OBJECTIVES: "Long COVID", a term coined by COVID-19 survivors, describes persistent or new symptoms in a subset of patients who have recovered from acute illness. Globally, the population of people infected with SARS-CoV-2 continues to expand rapidly, necessitating the need for a more thorough understanding of the array of potential sequelae of COVID-19. The multisystemic aspects of acute COVID-19 have been the subject of intense investigation, but the long-term complications remain poorly understood. Emerging data from lay press, social media, commentaries, and emerging scientific reports suggest that some COVID-19 survivors experience organ impairment and/or debilitating chronic symptoms, at times protean in nature, which impact their quality of life. METHODS/RESULTS: In this review, by addressing separately each body system, we describe the pleiotropic manifestations reported post COVID-19, their putative pathophysiology and risk factors, and attempt to offer guidance regarding work-up, follow-up and management strategies. Long term sequelae involve all systems with a negative impact on mental health, well-being and quality of life, while a subset of patients, report debilitating chronic fatigue, with or without other fluctuating or persistent symptoms, such as pain or cognitive dysfunction. Although the pathogenesis is unclear, residual damage from acute infection, persistent immune activation, mental factors, or unmasking of underlying co-morbidities are considered as drivers. Comparing long COVID with other post viral chronic syndromes may help to contextualize the complex somatic and emotional sequalae of acute COVID-19. The pace of recovery of different aspects of the syndrome remains unclear as the pandemic began only a year ago. CONCLUSIONS: Early recognition of long-term effects and thorough follow-up through dedicated multidisciplinary outpatient clinics with a carefully integrated research agenda are essential for treating COVID-19 survivors holistically. Twit Text FOAVip Epidemiology and organ specific sequelae of post-acute COVID19: A narrative review ????J Infect http://www.kidney.de/pget.php?&tw=1&pmid=33992686 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33992686 #FOAvip English Wikipedia <ref>{{Cite pmid|33992686}}</ref> Epidemiology and organ specific sequelae of post-acute COVID19: A narrative review #MMPMID33992686 Korompoki E; Gavriatopoulou M; Hicklen RS; Ntanasis-Stathopoulos I; Kastritis E; Fotiou D; Stamatelopoulos K; Terpos E; Kotanidou A; Hagberg CA; Dimopoulos MA; Kontoyiannis DP J Infect 2021[Jul]; 83 (1): 1-16 PMID33992686show ga OBJECTIVES: "Long COVID", a term coined by COVID-19 survivors, describes persistent or new symptoms in a subset of patients who have recovered from acute illness. Globally, the population of people infected with SARS-CoV-2 continues to expand rapidly, necessitating the need for a more thorough understanding of the array of potential sequelae of COVID-19. The multisystemic aspects of acute COVID-19 have been the subject of intense investigation, but the long-term complications remain poorly understood. Emerging data from lay press, social media, commentaries, and emerging scientific reports suggest that some COVID-19 survivors experience organ impairment and/or debilitating chronic symptoms, at times protean in nature, which impact their quality of life. METHODS/RESULTS: In this review, by addressing separately each body system, we describe the pleiotropic manifestations reported post COVID-19, their putative pathophysiology and risk factors, and attempt to offer guidance regarding work-up, follow-up and management strategies. Long term sequelae involve all systems with a negative impact on mental health, well-being and quality of life, while a subset of patients, report debilitating chronic fatigue, with or without other fluctuating or persistent symptoms, such as pain or cognitive dysfunction. Although the pathogenesis is unclear, residual damage from acute infection, persistent immune activation, mental factors, or unmasking of underlying co-morbidities are considered as drivers. Comparing long COVID with other post viral chronic syndromes may help to contextualize the complex somatic and emotional sequalae of acute COVID-19. The pace of recovery of different aspects of the syndrome remains unclear as the pandemic began only a year ago. CONCLUSIONS: Early recognition of long-term effects and thorough follow-up through dedicated multidisciplinary outpatient clinics with a carefully integrated research agenda are essential for treating COVID-19 survivors holistically. |*COVID-19/complications[MESH] |Humans[MESH] |Pandemics[MESH] |Post-Acute COVID-19 Syndrome[MESH] |Quality of Life[MESH]Epidemiology and organ specific sequelae of post-acute COVID19: A narr(epmc).pdf DeepDyve Pubget Overpricing