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10.1016/j.jviromet.2021.114153

http://scihub22266oqcxt.onion/10.1016/j.jviromet.2021.114153
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33984398!8108477!33984398
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suck abstract from ncbi


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pmid33984398      J+Virol+Methods 2021 ; 294 (ä): 114153
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  • Accessioning and automation compatible anterior nares swab design #MMPMID33984398
  • Pettit ME; Boswell SA; Qian J; Novak R; Springer M
  • J Virol Methods 2021[Aug]; 294 (ä): 114153 PMID33984398show ga
  • The COVID-19 pandemic has resulted in an unparalleled need for viral testing capacity across the world and is a critical requirement for successful re-opening of economies. The logistical barriers to near-universal testing are considerable. We have designed an injection molded polypropylene anterior nares swab, the Rhinostic, with a screw cap integrated into the swab handle that is compatible with fully automated sample accessioning and processing. The ability to collect and release both human and viral material is comparable to that of several commonly used swabs on the market. SARS-CoV-2 is stable on dry Rhinostic swabs for at least 3 days, even at 42 degrees C, and elution can be achieved with small volumes. To test the performance of the Rhinostic in patients, 119 samples were collected with Rhinostic and the positive and negative determinations were 100 % concordant with samples collected using Clinical Laboratory Improvement Amendments (CLIA) use approved nasal swabs at a clinical lab. The Rhinostic swab and barcoded tube set can be produced, sterilized, and packaged cost effectively and is designed to be adopted by clinical laboratories using automation to increase throughput and dramatically reduce the cost of a standard SARS-CoV-2 detection pipeline.
  • |Automation, Laboratory[MESH]
  • |COVID-19 Nucleic Acid Testing/*instrumentation/methods[MESH]
  • |Humans[MESH]
  • |Nasopharynx/anatomy & histology/*virology[MESH]
  • |Polypropylenes[MESH]
  • |RNA, Viral/*isolation & purification[MESH]
  • |SARS-CoV-2/*isolation & purification[MESH]


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