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10.1371/journal.pone.0251150

http://scihub22266oqcxt.onion/10.1371/journal.pone.0251150
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33983997!8118319!33983997
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suck abstract from ncbi


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pmid33983997      PLoS+One 2021 ; 16 (5): e0251150
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  • Effectiveness of thermal screening in detection of COVID-19 among truck drivers at Mutukula Land Point of Entry, Uganda #MMPMID33983997
  • Nsawotebba A; Ibanda I; Ssewanyana I; Ogwok P; Ocen F; Okiira C; Kagirita A; Mujuni D; Tugumisirize D; Kabugo J; Nyombi A; Majwala RK; Bagaya BS; Kalyesubula-Kibuuka S; Ssengooba W; Nabadda S
  • PLoS One 2021[]; 16 (5): e0251150 PMID33983997show ga
  • INTRODUCTION: Despite the limited evidence for its effectiveness, thermal screening at points of entry has increasingly become a standard protocol in numerous parts of the globe in response to the COVID-19 pandemic. We sought to determine the effectiveness of thermal screening as a key step in diagnosing COVID-19 in a resource-limited setting. MATERIALS AND METHODS: This was a retrospective cross-sectional study based on a review of body temperature and Xpert Xpress SARS CoV-2 test results records for truck drivers entering Uganda through Mutukula between 15th May and 30th July 2020. All records missing information for body temperature, age, gender, and Xpert Xpress SARS CoV-2 status were excluded from the data set. A data set of 7,181 entries was used to compare thermal screening and Xpert Xpress SARS CoV-2 assay test results using the diagnostic statistical test in STATAv15 software. The prevalence of COVID-19 amongst the truck drivers based on Xpert Xpress SARS CoV-2 assay results was determined. The sensitivity, specificity, positive predictive value, negative predictive value, positive and negative Likelihood ratios were obtained using Xpert Xpress SARS CoV-2 assay as the gold standard. RESULTS: Based on our gold standard test, the proportion of persons that tested positive for COVID-19 was 6.7% (95% CI: 6.1-7.3). Of the 7,181 persons that were thermally screened, 6,844 (95.3%) were male. The sample median age was 38 years (interquartile range, IQR: 31-45 years). The median body temperature was 36.5 degrees C (IQR: 36.3-36.7) and only n (1.2%) had a body temperature above 37.5 degrees C. The sensitivity and specificity of thermal screening were 9.9% (95% CI: 7.4-13.0) and 99.5% (95% CI: 99.3-99.6) respectively. The positive and negative predictive values were 57.8 (95% CI: 46.5-68.6) and 93.9 (95% CI: 93.3-94.4) respectively. The positive and negative Likelihood Ratios (LRs) were 19 (95% CI: 12.4-29.1) and 0.9 (95% CI: 0.88-0.93) respectively. CONCLUSION: In this study population, the use of Thermal screening alone is ineffective in the detection of potential COVID-19 cases at point of entry. We recommend a combination of screening tests or additional testing using highly sensitive molecular diagnostics such as Polymerase Chain Reaction.
  • |Adult[MESH]
  • |Body Temperature[MESH]
  • |COVID-19/*diagnosis[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Mass Screening[MESH]
  • |Middle Aged[MESH]
  • |Predictive Value of Tests[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2/isolation & purification[MESH]
  • |Uganda/epidemiology[MESH]


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