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10.1007/s15010-021-01610-z

http://scihub22266oqcxt.onion/10.1007/s15010-021-01610-z
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33983624!8117126!33983624
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suck abstract from ncbi


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pmid33983624      Infection 2021 ; 49 (5): 907-916
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  • COVID-19 is not "just another flu": a real-life comparison of severe COVID-19 and influenza in hospitalized patients in Vienna, Austria #MMPMID33983624
  • Pawelka E; Karolyi M; Mader T; Omid S; Kelani H; Baumgartner S; Ely S; Hoepler W; Jilma B; Koenig F; Laferl H; Traugott M; Turner M; Seitz T; Wenisch C; Zoufaly A
  • Infection 2021[Oct]; 49 (5): 907-916 PMID33983624show ga
  • BACKGROUND: COVID-19 is regularly compared to influenza. Mortality and case-fatality rates vary widely depending on incidence of COVID-19 and the testing policy in affected countries. To date, data comparing hospitalized patients with COVID-19 and influenza is scarce. METHODS: Data from patients with COVID-19 were compared to patients infected with influenza A (InfA) and B (InfB) virus during the 2017/18 and 2018/19 seasons. All patients were >/= 18 years old, had PCR-confirmed infection and needed hospital treatment. Demographic data, medical history, length-of-stay (LOS), complications including in-hospital mortality were analyzed. RESULTS: In total, 142 patients with COVID-19 were compared to 266 patients with InfA and 300 with InfB. Differences in median age (COVID-19 70.5 years vs InfA 70 years and InfB 77 years, p < 0.001) and laboratory results were observed. COVID-19 patients had fewer comorbidities, but complications (respiratory insufficiency, pneumonia, acute kidney injury, acute heart failure and death) occurred more frequently. Median length-of-stay (LOS) was longer in COVID-19 patients (12 days vs InfA 7 days vs. InfB 7 days, p < 0.001). There was a fourfold higher in-hospital mortality in COVID-19 patients (23.2%) when compared with InfA (5.6%) or InfB (4.7%; p < 0.001). CONCLUSION: In hospitalized patients, COVID-19 is associated with longer LOS, a higher number of complications and higher in-hospital mortality compared to influenza, even in a population with fewer co-morbidities. This data, a high reproduction number and limited treatment options, alongside excess mortality during the SARS-CoV-2 pandemic, support the containment strategies implemented by most authorities.
  • |*COVID-19[MESH]
  • |*Influenza, Human/epidemiology[MESH]
  • |Adolescent[MESH]
  • |Austria[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]


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