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10.1177/08903344211018185

http://scihub22266oqcxt.onion/10.1177/08903344211018185
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33982613!ä!33982613

suck abstract from ncbi


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pmid33982613      J+Hum+Lact 2021 ; 37 (3): 469-476
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  • Antibodies Against SARS-CoV-2 in Human Milk: Milk Conversion Rates in the Netherlands #MMPMID33982613
  • Juncker HG; Romijn M; Loth VN; Ruhe EJM; Bakker S; Kleinendorst S; de Groot CJM; Pajkrt D; Korosi A; van Goudoever JB; van Gils MJ; van Keulen BJ
  • J Hum Lact 2021[Aug]; 37 (3): 469-476 PMID33982613show ga
  • BACKGROUND: It has been demonstrated that human milk from mothers who have been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains antibodies against the virus, which could play an important role in protecting the recipient infant against coronavirus disease 2019 (COVID-19). Seroconversion is measured frequently around the world, but the milk conversion rate is unknown. RESEARCH AIMS: To determine (1) the prevalence and (2) the dynamics of immunoglobulin A (IgA) antibodies against SARS-CoV-2 in human milk amongst lactating mothers in the Netherlands. METHODS: In this large prospective cohort study, lactating mothers (N = 2312) were included between October 12, 2020 and February 24, 2021. Enzyme-linked immunosorbent assay was used to determine levels of IgA antibodies in human milk and immunoglobulin G (IgG) antibodies in serum against the ectodomain of the SARS-CoV-2 spike protein. RESULTS: A total of 691 (30.6%) participants had SARS-CoV-2 specific antibodies in human milk and/or serum. Of these participants, 524 (23.1%) had IgA antibodies against SARS-CoV-2 in human milk, and 356 (15.7%) had IgG antibodies against SARS-CoV-2 in serum. A total of 199 (8.8%) participants had antibodies in both human milk and serum. SARS-CoV-2 specific IgA antibodies in human milk remain present at least 10 months after a polymerase chain reaction confirmed infection. CONCLUSION: The prevalence of IgA antibodies against SARS-CoV-2 in human milk was 23.1% in our cohort. This high prevalence of antibodies in human milk might lead to passive immunity in many breastfed infants and may serve as protection against COVID-19.
  • |*COVID-19[MESH]
  • |*SARS-CoV-2[MESH]
  • |Antibodies, Viral[MESH]
  • |Breast Feeding[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Lactation[MESH]
  • |Milk, Human[MESH]
  • |Netherlands/epidemiology[MESH]
  • |Prospective Studies[MESH]


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