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10.1136/medethics-2021-107229 http://scihub22266oqcxt.onion/10.1136/medethics-2021-107229 33980657!ä!33980657 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Med+Ethics 2021 ; 47 (8): 539-542 Nephropedia Template TP {{tp|p=33980657|t=2021. COVID-19 controlled human infection studies: worries about local community impact and demands for local engagement |pdf=|usr=}}{{33980657}} gab.com Text COVID-19 controlled human infection studies: worries about local community impact and demands for local engagement JO: J Med Ethics http://www.kidney.de/pget.php?&tw=1&pmid=33980657 #FOAvip In spring, summer and autumn 2020, one abiding argument against controlled human infection (CHI) studies of SARS-CoV-2 vaccines has been their impact on local communities. Leading scientists and bioethicists expressed concern about undue usage of local residents' direly needed scarce resources at a time of great need and even about their unintended infection. They recommended either avoiding CHI trials or engaging local communities before conducting any CHIs. Similar recommendations were not made for the alternative-standard phase III field trials of these same vaccines. We argue that the health effects of CHI studies on local residents not participating in the study tend to be smaller and more positive than those of field trials. That is all the more so now that tested vaccines are being rolled out. Whether or not local community engagement is necessary for urgent vaccine studies in the pandemic, the case for its engagement is stronger prior to field trials than prior to CHI studies. Twit Text FOAVip COVID-19 controlled human infection studies: worries about local community impact and demands for local engagement ????J Med Ethics http://www.kidney.de/pget.php?&tw=1&pmid=33980657 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33980657 #FOAvip English Wikipedia <ref>{{Cite pmid|33980657}}</ref> COVID-19 controlled human infection studies: worries about local community impact and demands for local engagement #MMPMID33980657 Lee K; Eyal N J Med Ethics 2021[Aug]; 47 (8): 539-542 PMID33980657show ga In spring, summer and autumn 2020, one abiding argument against controlled human infection (CHI) studies of SARS-CoV-2 vaccines has been their impact on local communities. Leading scientists and bioethicists expressed concern about undue usage of local residents' direly needed scarce resources at a time of great need and even about their unintended infection. They recommended either avoiding CHI trials or engaging local communities before conducting any CHIs. Similar recommendations were not made for the alternative-standard phase III field trials of these same vaccines. We argue that the health effects of CHI studies on local residents not participating in the study tend to be smaller and more positive than those of field trials. That is all the more so now that tested vaccines are being rolled out. Whether or not local community engagement is necessary for urgent vaccine studies in the pandemic, the case for its engagement is stronger prior to field trials than prior to CHI studies. |*COVID-19 Vaccines[MESH] |*Community Participation[MESH] |*Research Design[MESH] |COVID-19/epidemiology/*psychology/*transmission[MESH] |Humans[MESH] |Pandemics[MESH]COVID-19 controlled human infection studies: worries about local commu(epmc).pdf DeepDyve Pubget Overpricing