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10.1002/cti2.1281 http://scihub22266oqcxt.onion/10.1002/cti2.1281 33976879!8101693!33976879     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Transl+Immunology 2021 ; 10 (5): e1281 Nephropedia Template TP {{tp|p=33976879|t=2021. Heterogeneous magnitude of immunological memory to SARS-CoV-2 in recovered individuals |pdf=|usr=}}{{33976879}} gab.com Text Heterogeneous magnitude of immunological memory to SARS-CoV-2 in recovered individuals JO: Clin Transl Immunology http://www.kidney.de/pget.php?&tw=1&pmid=33976879 #FOAvip OBJECTIVE: Although the adaptive immune response to SARS-CoV-2 has been characterised in the acute and early convalescent phase of the disease, few studies explore whether natural infection elicits long-lasting immunological memory in recovered individuals. In this work, we aimed to assess the maintenance of immunological memory to SARS-CoV-2. METHODS: We evaluated the long-term virus-specific cellular and humoral immune response in the members of an Italian Serie A football team, who experienced a cluster of COVID-19 in March 2020, which was strictly evaluated in the following months. RESULTS: Our results highlight a heterogeneous magnitude of immunological memory at 5 months after infection. Indeed, 20% of the subjects displayed a weak cellular and humoral memory to SARS-CoV-2, suggesting that they may be at higher risk of reinfection. In addition, a history of symptomatic COVID-19 was associated with higher levels of SARS-CoV-2-reactive CD4(+) T cells and specific antibody levels than in asymptomatic individuals. CONCLUSION: Collectively, these data demonstrate that immunity to SARS-CoV-2 is maintained five months postinfection even if the magnitude of response is heterogeneous among individuals. This finding suggests that some COVID-19-recovered subjects may benefit from vaccination. Twit Text FOAVip Heterogeneous magnitude of immunological memory to SARS-CoV-2 in recovered individuals ????Clin Transl Immunology http://www.kidney.de/pget.php?&tw=1&pmid=33976879 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33976879 #FOAvip English Wikipedia <ref>{{Cite pmid|33976879}}</ref> Heterogeneous magnitude of immunological memory to SARS-CoV-2 in recovered individuals #MMPMID33976879 Mazzoni A; Maggi L; Capone M; Vanni A; Spinicci M; Salvati L; Tekle Kiros S; Semeraro R; Pengue L; Colao MG; Magi A; Rossolini GM; Liotta F; Cosmi L; Bartoloni A; Annunziato F Clin Transl Immunology 2021[]; 10 (5): e1281 PMID33976879show ga OBJECTIVE: Although the adaptive immune response to SARS-CoV-2 has been characterised in the acute and early convalescent phase of the disease, few studies explore whether natural infection elicits long-lasting immunological memory in recovered individuals. In this work, we aimed to assess the maintenance of immunological memory to SARS-CoV-2. METHODS: We evaluated the long-term virus-specific cellular and humoral immune response in the members of an Italian Serie A football team, who experienced a cluster of COVID-19 in March 2020, which was strictly evaluated in the following months. RESULTS: Our results highlight a heterogeneous magnitude of immunological memory at 5 months after infection. Indeed, 20% of the subjects displayed a weak cellular and humoral memory to SARS-CoV-2, suggesting that they may be at higher risk of reinfection. In addition, a history of symptomatic COVID-19 was associated with higher levels of SARS-CoV-2-reactive CD4(+) T cells and specific antibody levels than in asymptomatic individuals. CONCLUSION: Collectively, these data demonstrate that immunity to SARS-CoV-2 is maintained five months postinfection even if the magnitude of response is heterogeneous among individuals. This finding suggests that some COVID-19-recovered subjects may benefit from vaccination. äHeterogeneous magnitude of immunological memory to SARS-CoV-2 in recov(epmc).pdf DeepDyve Pubget Overpricing