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10.1038/s41598-021-89236-x

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33972607!8110575!33972607
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suck abstract from ncbi


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pmid33972607      Sci+Rep 2021 ; 11 (1): 9819
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  • Feasibility of large-scale population testing for SARS-CoV-2 detection by self-testing at home #MMPMID33972607
  • Iruzubieta P; Fernandez-Lanas T; Rasines L; Cayon L; Alvarez-Cancelo A; Santos-Laso A; Garcia-Blanco A; Curiel-Olmo S; Cabezas J; Wallmann R; Fabrega E; Martinez-Taboada VM; Hernandez JL; Lopez-Hoyos M; Lazarus JV; Crespo J
  • Sci Rep 2021[May]; 11 (1): 9819 PMID33972607show ga
  • The simplicity and low cost of rapid point-of-care tests greatly facilitate large-scale population testing, which can contribute to controlling the spread of the COVID-19 virus. We evaluated the applicability of a self-testing strategy for SARS-CoV2 in a population-based, cross-sectional study in Cantabria, Spain, between April and May 2020. For the self-testing strategy, participants received the necessary material for the self-collection of blood and performance of a rapid antibody test using lateral flow immunoassay at home without the supervision of healthcare personnel. A total of 1,022 participants were enrolled. Most participants correctly performed the COVID-19 self-test the first time (91.3% [95% CI 89.4-92.9]). Only a minority of the participants (0.7%) needed the help of healthcare personnel, while 6.9% required a second kit delivery, for a total valid test result in 96.9% of the participants. Incorrect use of the self-test was not associated with the educational level, age over 65, or housing area. Prevalence of IgG antibodies against SARS-CoV2 for subjects with a valid rapid test result was 3.1% (95% CI 2.2-4.4), similar to the seroprevalence result obtained using a conventional approach carried out by healthcare professionals. In conclusion, COVID-19 self-testing should be considered as a screening tool.
  • |*Self-Testing[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19/*diagnosis/virology[MESH]
  • |Cohort Studies[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Feasibility Studies[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunoglobulin G[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |SARS-CoV-2/*isolation & purification/physiology[MESH]
  • |Spain[MESH]


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