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10.1038/s41392-021-00596-2 http://scihub22266oqcxt.onion/10.1038/s41392-021-00596-2 33972497!8107204!33972497     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Signal+Transduct+Target+Ther 2021 ; 6 (1): 181 Nephropedia Template TP {{tp|p=33972497|t=2021. Viral dynamics and antibody responses in people with asymptomatic SARS-CoV-2 infection |pdf=|usr=}}{{33972497}} gab.com Text Viral dynamics and antibody responses in people with asymptomatic SARS-CoV-2 infection JO: Signal Transduct Target Ther http://www.kidney.de/pget.php?&tw=1&pmid=33972497 #FOAvip Over 40% of the coronavirus disease 2019 (COVID-19) COVID-19 patients were asymptomatically infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the immune responses of these asymptomatic individuals is a critical factor for developing the strategy to contain the COVID-19 pandemic. Here, we determined the viral dynamics and antibody responses among 143 asymptomatic individuals identified in a massive screening of more than 5 million people in eight districts of Wuhan in May 2020. Asymptomatic individuals were admitted to the government-designated centralized sites in accordance with policy. The incidence rate of asymptomatic infection is ~2.92/100,000. These individuals had low viral copy numbers (peaked at 315 copies/mL) and short-lived antibody responses with the estimated diminish time of 69 days. The antibody responses in individuals with persistent SARS-CoV-2 infection is much longer with the estimated diminish time of 257 days. These results imply that the immune responses in the asymptomatic individuals are not potent enough for preventing SARS-CoV-2 re-infection, which has recently been reported in recovered COVID-19 patients. This casts doubt on the efficacy of forming "herd-immunity" through natural SARS-CoV-2 infection and urges for the development of safe and effective vaccines. Twit Text FOAVip Viral dynamics and antibody responses in people with asymptomatic SARS-CoV-2 infection ????Signal Transduct Target Ther http://www.kidney.de/pget.php?&tw=1&pmid=33972497 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33972497 #FOAvip English Wikipedia <ref>{{Cite pmid|33972497}}</ref> Viral dynamics and antibody responses in people with asymptomatic SARS-CoV-2 infection #MMPMID33972497 Sui Z; Dai X; Lu Q; Zhang Y; Huang M; Li S; Peng T; Xie J; Zhang Y; Wu C; Xia J; Dong L; Yang J; Huang W; Liu S; Wang Z; Li K; Yang Q; Zhou X; Wu Y; Liu W; Fang X; Peng K Signal Transduct Target Ther 2021[May]; 6 (1): 181 PMID33972497show ga Over 40% of the coronavirus disease 2019 (COVID-19) COVID-19 patients were asymptomatically infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the immune responses of these asymptomatic individuals is a critical factor for developing the strategy to contain the COVID-19 pandemic. Here, we determined the viral dynamics and antibody responses among 143 asymptomatic individuals identified in a massive screening of more than 5 million people in eight districts of Wuhan in May 2020. Asymptomatic individuals were admitted to the government-designated centralized sites in accordance with policy. The incidence rate of asymptomatic infection is ~2.92/100,000. These individuals had low viral copy numbers (peaked at 315 copies/mL) and short-lived antibody responses with the estimated diminish time of 69 days. The antibody responses in individuals with persistent SARS-CoV-2 infection is much longer with the estimated diminish time of 257 days. These results imply that the immune responses in the asymptomatic individuals are not potent enough for preventing SARS-CoV-2 re-infection, which has recently been reported in recovered COVID-19 patients. This casts doubt on the efficacy of forming "herd-immunity" through natural SARS-CoV-2 infection and urges for the development of safe and effective vaccines. |Aged[MESH] |Antibodies, Viral/blood/genetics/*immunology[MESH] |Asymptomatic Infections/*epidemiology[MESH] |COVID-19/blood/*immunology/physiopathology/virology[MESH] |China/epidemiology[MESH] |Female[MESH] |Humans[MESH] |Immunity/*immunology[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH]Viral dynamics and antibody responses in people with asymptomatic SARS(epmc).pdf DeepDyve Pubget Overpricing