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10.1007/s11302-021-09771-0 http://scihub22266oqcxt.onion/10.1007/s11302-021-09771-0 33970408!8107773!33970408     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Purinergic+Signal 2021 ; 17 (3): 399-410 Nephropedia Template TP {{tp|p=33970408|t=2021. Cystic fibrosis improves COVID-19 survival and provides clues for treatment of SARS-CoV-2 |pdf=|usr=}}{{33970408}} gab.com Text Cystic fibrosis improves COVID-19 survival and provides clues for treatment of SARS-CoV-2 JO: Purinergic Signal http://www.kidney.de/pget.php?&tw=1&pmid=33970408 #FOAvip Systemic pools of ATP are elevated in individuals homozygous for cystic fibrosis (CF) as evidenced by elevated blood and plasma ATP levels. This elevated ATP level seems to provide benefit in the presence of advanced solid tumors (Abraham et al., Nature Medicine 2(5):593-596, 1996). We published in this journal a paper showing that IV ATP can elevate the depleted ATP pools of advanced cancer patients up to levels found in CF patients with subsequent clinical, biochemical, and quality of life (QOL) improvements (Rapaport et al., Purinergic Signalling 11(2): 251-262, 2015). We hypothesize that the elevated ATP levels seen in CF patients may be benefiting CF patients in another way: by improving their survival after contracting COVID-19. We discuss here the reasoning behind this hypothesis and suggest how these findings might be applied clinically in the general population. Twit Text FOAVip Cystic fibrosis improves COVID-19 survival and provides clues for treatment of SARS-CoV-2 ????Purinergic Signal http://www.kidney.de/pget.php?&tw=1&pmid=33970408 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33970408 #FOAvip English Wikipedia <ref>{{Cite pmid|33970408}}</ref> Cystic fibrosis improves COVID-19 survival and provides clues for treatment of SARS-CoV-2 #MMPMID33970408 Abraham EH; Guidotti G; Rapaport E; Bower D; Brown J; Griffin RJ; Donnelly A; Waitzkin ED; Qamar K; Thompson MA; Ethirajan S; Robinson K Purinergic Signal 2021[Sep]; 17 (3): 399-410 PMID33970408show ga Systemic pools of ATP are elevated in individuals homozygous for cystic fibrosis (CF) as evidenced by elevated blood and plasma ATP levels. This elevated ATP level seems to provide benefit in the presence of advanced solid tumors (Abraham et al., Nature Medicine 2(5):593-596, 1996). We published in this journal a paper showing that IV ATP can elevate the depleted ATP pools of advanced cancer patients up to levels found in CF patients with subsequent clinical, biochemical, and quality of life (QOL) improvements (Rapaport et al., Purinergic Signalling 11(2): 251-262, 2015). We hypothesize that the elevated ATP levels seen in CF patients may be benefiting CF patients in another way: by improving their survival after contracting COVID-19. We discuss here the reasoning behind this hypothesis and suggest how these findings might be applied clinically in the general population. |*COVID-19[MESH] |Adenosine Triphosphate/*metabolism[MESH] |Cystic Fibrosis/*complications/*metabolism/*physiopathology[MESH] |Humans[MESH]Cystic fibrosis improves COVID-19 survival and provides clues for trea(epmc).pdf DeepDyve Pubget Overpricing