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10.1016/j.ijid.2021.05.001 http://scihub22266oqcxt.onion/10.1016/j.ijid.2021.05.001 33965598!8119437!33965598     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Infect+Dis 2021 ; 107 (ä): 232-233 Nephropedia Template TP {{tp|p=33965598|t=2021. Potential value of circulating endothelial cells for the diagnosis and treatment of COVID-19 |pdf=|usr=}}{{33965598}} gab.com Text Potential value of circulating endothelial cells for the diagnosis and treatment of COVID-19 JO: Int J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=33965598 #FOAvip The ongoing severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic has been a formidable global challenge. As yet, there are very few drugs to treat this infection and no vaccine is currently available. It has gradually become apparant that coronavirus disease 2019 (COVID-19) is not a simple disease involving a single organ; rather, many vital organs and systems are affected. The endothelium is one target of SARS-CoV-2. Damaged endothelial cells, which break away from organs and enter the bloodstream to form circulating endothelial cells, were recently reported as putative biomarkers for COVID-19. Modulation of the expression level of sphingosine-1 phosphate via sphingosine kinase activation can control endothelial cell proliferation and apoptosis. As such, it may be possible to obtain a sensitive and specific diagnosis of the severity of COVID-19 by assessing the absolute number and the viable/apoptotic ratio of circulating endothelial cells. Furthermore, a focus on the endothelium could help to develop a strategy for COVID-19 treatment from the perspective of endothelial protection and repair. Twit Text FOAVip Potential value of circulating endothelial cells for the diagnosis and treatment of COVID-19 ????Int J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=33965598 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33965598 #FOAvip English Wikipedia <ref>{{Cite pmid|33965598}}</ref> Potential value of circulating endothelial cells for the diagnosis and treatment of COVID-19 #MMPMID33965598 Zhang X; Jiang M; Yang J Int J Infect Dis 2021[Jun]; 107 (ä): 232-233 PMID33965598show ga The ongoing severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic has been a formidable global challenge. As yet, there are very few drugs to treat this infection and no vaccine is currently available. It has gradually become apparant that coronavirus disease 2019 (COVID-19) is not a simple disease involving a single organ; rather, many vital organs and systems are affected. The endothelium is one target of SARS-CoV-2. Damaged endothelial cells, which break away from organs and enter the bloodstream to form circulating endothelial cells, were recently reported as putative biomarkers for COVID-19. Modulation of the expression level of sphingosine-1 phosphate via sphingosine kinase activation can control endothelial cell proliferation and apoptosis. As such, it may be possible to obtain a sensitive and specific diagnosis of the severity of COVID-19 by assessing the absolute number and the viable/apoptotic ratio of circulating endothelial cells. Furthermore, a focus on the endothelium could help to develop a strategy for COVID-19 treatment from the perspective of endothelial protection and repair. |*SARS-CoV-2[MESH] |Biomarkers[MESH] |COVID-19/*diagnosis/therapy[MESH] |Cystic Fibrosis Transmembrane Conductance Regulator/physiology[MESH] |Endothelial Cells/*pathology[MESH] |Humans[MESH] |Lysophospholipids/analysis[MESH]Potential value of circulating endothelial cells for the diagnosis and(epmc).pdf DeepDyve Pubget Overpricing