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10.1111/acps.13314

http://scihub22266oqcxt.onion/10.1111/acps.13314
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33960406!8212113!33960406
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suck abstract from ncbi


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pmid33960406      Acta+Psychiatr+Scand 2021 ; 144 (3): 238-245
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  • Effectiveness of maintenance electroconvulsive therapy-Evidence from modifications due to the COVID-19 pandemic #MMPMID33960406
  • Methfessel I; Besse M; Belz M; Zilles-Wegner D
  • Acta Psychiatr Scand 2021[Sep]; 144 (3): 238-245 PMID33960406show ga
  • OBJECTIVE: Continuation and maintenance ECT (c-/m-ECT) are effective in the prevention of relapse and recurrence of both affective and psychotic disorders. However, data are scarce concerning the trajectories of severe mental disorders after the end of c-/m-ECT. This prospective study investigates the clinical outcome of patients with versus without modifications of their c-/m-ECT schedules. METHODS: In the context of the COVID-19 pandemic, ECT capacities were restricted at many clinics in early 2020. All patients receiving c-/m-ECT in March and April 2020 at our department (n = 53, unipolar depression, bipolar disorder, schizophrenia) were followed up for six months to investigate the impact of treatment modifications imposed by the pandemic. Based on individual decisions, c-/m-ECT was either (a) continued without modification, (b) continued with reduced frequency, or (c) discontinued. RESULTS: Both reduced frequency and discontinuation of c-/m-ECT were associated with significant clinical deterioration as measured by CGI-I (Clinical Global Impression Scale - Global Improvement) during the six-month follow-up when compared to the subgroup of patients without any treatment modification (p = 0.005, p = 0.011). Furthermore, patients with discontinued or reduced c-/m-ECT showed significantly higher rates of rehospitalizations (p = 0.028) and new acute courses of ECT (p = 0.018). CONCLUSION: Despite the limitations of a heterogeneous and relatively small sample, our study strongly corroborates the effectiveness of c-/m-ECT in a real-world population. Especially, patients with shorter time since index ECT seem to be at high risk for severe clinical deterioration in the case of treatment discontinuation or reduction.
  • |*COVID-19[MESH]
  • |*Electroconvulsive Therapy[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Prospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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