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10.3389/fphar.2021.652688 http://scihub22266oqcxt.onion/10.3389/fphar.2021.652688 33959018!8094534!33959018     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Pharmacol 2021 ; 12 (ä): 652688 Nephropedia Template TP {{tp|p=33959018|t=2021. Fluvoxamine: A Review of Its Mechanism of Action and Its Role in COVID-19 |pdf=|usr=}}{{33959018}} gab.com Text Fluvoxamine: A Review of Its Mechanism of Action and Its Role in COVID-19 JO: Front Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=33959018 #FOAvip Fluvoxamine is a well-tolerated, widely available, inexpensive selective serotonin reuptake inhibitor that has been shown in a small, double-blind, placebo-controlled, randomized study to prevent clinical deterioration of patients with mild coronavirus disease 2019 (COVID-19). Fluvoxamine is also an agonist for the sigma-1 receptor, through which it controls inflammation. We review here a body of literature that shows important mechanisms of action of fluvoxamine and other SSRIs that could play a role in COVID-19 treatment. These effects include: reduction in platelet aggregation, decreased mast cell degranulation, interference with endolysosomal viral trafficking, regulation of inositol-requiring enzyme 1alpha-driven inflammation and increased melatonin levels, which collectively have a direct antiviral effect, regulate coagulopathy or mitigate cytokine storm, which are known hallmarks of severe COVID-19. Twit Text FOAVip Fluvoxamine: A Review of Its Mechanism of Action and Its Role in COVID-19 ????Front Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=33959018 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33959018 #FOAvip English Wikipedia <ref>{{Cite pmid|33959018}}</ref> Fluvoxamine: A Review of Its Mechanism of Action and Its Role in COVID-19 #MMPMID33959018 Sukhatme VP; Reiersen AM; Vayttaden SJ; Sukhatme VV Front Pharmacol 2021[]; 12 (ä): 652688 PMID33959018show ga Fluvoxamine is a well-tolerated, widely available, inexpensive selective serotonin reuptake inhibitor that has been shown in a small, double-blind, placebo-controlled, randomized study to prevent clinical deterioration of patients with mild coronavirus disease 2019 (COVID-19). Fluvoxamine is also an agonist for the sigma-1 receptor, through which it controls inflammation. We review here a body of literature that shows important mechanisms of action of fluvoxamine and other SSRIs that could play a role in COVID-19 treatment. These effects include: reduction in platelet aggregation, decreased mast cell degranulation, interference with endolysosomal viral trafficking, regulation of inositol-requiring enzyme 1alpha-driven inflammation and increased melatonin levels, which collectively have a direct antiviral effect, regulate coagulopathy or mitigate cytokine storm, which are known hallmarks of severe COVID-19. äFluvoxamine: A Review of Its Mechanism of Action and Its Role in COVID(epmc).pdf DeepDyve Pubget Overpricing