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10.1016/j.mayocp.2021.03.015

http://scihub22266oqcxt.onion/10.1016/j.mayocp.2021.03.015
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33958053!7997730!33958053
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suck abstract from ncbi


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pmid33958053      Mayo+Clin+Proc 2021 ; 96 (5): 1165-1174
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  • Prevalence of SARS-CoV-2 Antibodies in a Multistate Academic Medical Center #MMPMID33958053
  • Carter RE; Theel ES; Breeher LE; Swift MD; Van Brunt NA; Smith WR; Blanchfield LL; Daugherty EA; Chapital AB; Matson KM; Bews KA; Johnson PW; Domnick RA; Joyce DE; Geyer HL; Granger D; Hilgart HR; Turgeon CT; Sanders KA; Matern D; Nassar A; Sampathkumar P; Hainy CM; Orford RR; Vachon CM; Didehban R; Morice WG; Ting HH; Williams AW; Gray RJ; Thielen KR; Farrugia G
  • Mayo Clin Proc 2021[May]; 96 (5): 1165-1174 PMID33958053show ga
  • OBJECTIVE: To estimate the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in health care personnel. METHODS: The Mayo Clinic Serology Screening Program was created to provide a voluntary, two-stage testing program for SARS-CoV-2 antibodies to health care personnel. The first stage used a dried blood spot screening test initiated on June 15, 2020. Those participants identified as reactive were advised to have confirmatory testing via a venipuncture. Venipuncture results through August 8, 2020, were considered. Consent and authorization for testing was required to participate in the screening program. This report, which was conducted under an institutional review board-approved protocol, only includes employees who have further authorized their records for use in research. RESULTS: A total of 81,113 health care personnel were eligible for the program, and of these 29,606 participated in the screening program. A total of 4284 (14.5%) of the dried blood spot test results were "reactive" and warranted confirmatory testing. Confirmatory testing was completed on 4094 (95.6%) of the screen reactive with an overall seroprevalence rate of 0.60% (95% CI, 0.52% to 0.69%). Significant variation in seroprevalence was observed by region of the country and age group. CONCLUSION: The seroprevalence for SARS-CoV-2 antibodies through August 8, 2020, was found to be lower than previously reported in other health care organizations. There was an observation that seroprevalence may be associated with community disease burden.
  • |*COVID-19 Serological Testing/methods/statistics & numerical data[MESH]
  • |*COVID-19/blood/epidemiology/therapy[MESH]
  • |*SARS-CoV-2/immunology/isolation & purification[MESH]
  • |Academic Medical Centers[MESH]
  • |Adult[MESH]
  • |Antibodies, Viral/*blood[MESH]
  • |Disease Transmission, Infectious/*statistics & numerical data[MESH]
  • |Female[MESH]
  • |Health Personnel/*statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Immunoglobulin G/blood[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Public Health/methods[MESH]
  • |Seroepidemiologic Studies[MESH]
  • |Spatio-Temporal Analysis[MESH]


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