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10.21873/anticanres.15050

http://scihub22266oqcxt.onion/10.21873/anticanres.15050
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33952500!ä!33952500

suck abstract from ncbi


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pmid33952500      Anticancer+Res 2021 ; 41 (5): 2689-2696
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  • Advanced Stages and Increased Need for Adjuvant Treatments in Breast Cancer Patients: The Effect of the One-year COVID-19 Pandemic #MMPMID33952500
  • Vanni G; Pellicciaro M; Materazzo M; Pedini D; Portarena I; Buonomo C; Perretta T; Rizza S; Pistolese CA; Buonomo OC
  • Anticancer Res 2021[May]; 41 (5): 2689-2696 PMID33952500show ga
  • BACKGROUND/AIM: The COVID-19 lockdown includes restrictive measures and temporary health system reorganization. Resources were shifted to COVID-19 patients, screening programs were temporary suspended, and oncological care suffered slow-down. The aim of the study was to evaluate the impact of these measures on breast cancer patients. PATIENTS AND METHODS: All breast cancer patients referred to our unit from February 21, 2019 to February 21, 2021 were enrolled. Type of treatments and surgery, TNM, tumor diameter, and predictive and prognostic factors were analyzed. RESULTS: Out of 445 patients with a breast cancer diagnosis, 182 (40.9%) were enrolled in the COVID-19 group (from February 21, 2010 to February 21, 2021). These patients were compared with 263 (59.1%) patients pre-COVID-19. Tumor diameters were bigger in the COVID-19 group. Type of surgery and N staging were statistically significantly different. Extreme advanced disease incidence was significantly different between the groups (2.7% COVID-19 group vs. 0 pre-COVID-19 group, p=0.011). Incidence of post-surgical radiation-therapy was higher in the COVID-19 group. Other variables analyzed were comparable without a statistically significant difference. CONCLUSION: COVID-19 led to increased tumor dimensions, advanced N-staging, and increased need for adjuvant treatments in breast cancer.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Breast Neoplasms/diagnosis/epidemiology/*pathology/*therapy[MESH]
  • |COVID-19/*epidemiology/prevention & control/psychology[MESH]
  • |Combined Modality Therapy[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Lymphatic Metastasis[MESH]
  • |Male[MESH]
  • |Mastectomy[MESH]
  • |Middle Aged[MESH]
  • |Neoplasm Staging[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]
  • |Time-to-Treatment[MESH]


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