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10.1177/09636897211010632 http://scihub22266oqcxt.onion/10.1177/09636897211010632 33949207!8114753!33949207     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Transplant 2021 ; 30 (ä): 9636897211010632 Nephropedia Template TP {{tp|p=33949207|t=2021. Role of the Immune Microenvironment in SARS-CoV-2 Infection |pdf=|usr=}}{{33949207}} gab.com Text Role of the Immune Microenvironment in SARS-CoV-2 Infection JO: Cell Transplant http://www.kidney.de/pget.php?&tw=1&pmid=33949207 #FOAvip Severe acute respiratory syndrome coronavirus (SARS-CoV-2) first emerged in December 2019 in Wuhan, China, and has since spread rapidly worldwide. As researchers seek to learn more about COVID-19, the disease it causes, this novel virus continues to infect and kill. Despite the socioeconomic impacts of SARS-CoV-2 infections and likelihood of future outbreaks of other pathogenic coronaviruses, options to prevent or treat coronavirus infections remain limited. In current clinical trials, potential coronavirus treatments focusing on killing the virus or on preventing infection using vaccines largely ignore the host immune response. The relatively small body of current research on the virus indicates pathological responses by the immune system as the leading cause for much of the morbidity and mortality caused by COVID-19. In this review, we investigated the host innate and adaptive immune responses against COVID-19, collated information on recent COVID-19 experimental data, and summarized the systemic immune responses to and histopathology of SARS-CoV-2 infection. Finally, we summarized the immune-related biomarkers to define patients with high-risk and worst-case outcomes, and identified the possible usefulness of inflammatory markers as potential immunotherapeutic targets. This review provides an overview of current knowledge on COVID-19 and the symptomatological differences between healthy, convalescent, and severe cohorts, while offering research directions for alternative immunoregulation therapeutic targets. Twit Text FOAVip Role of the Immune Microenvironment in SARS-CoV-2 Infection ????Cell Transplant http://www.kidney.de/pget.php?&tw=1&pmid=33949207 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33949207 #FOAvip English Wikipedia <ref>{{Cite pmid|33949207}}</ref> Role of the Immune Microenvironment in SARS-CoV-2 Infection #MMPMID33949207 Ye CH; Hsu WL; Peng GR; Yu WC; Lin WC; Hu S; Yu SH Cell Transplant 2021[Jan]; 30 (ä): 9636897211010632 PMID33949207show ga Severe acute respiratory syndrome coronavirus (SARS-CoV-2) first emerged in December 2019 in Wuhan, China, and has since spread rapidly worldwide. As researchers seek to learn more about COVID-19, the disease it causes, this novel virus continues to infect and kill. Despite the socioeconomic impacts of SARS-CoV-2 infections and likelihood of future outbreaks of other pathogenic coronaviruses, options to prevent or treat coronavirus infections remain limited. In current clinical trials, potential coronavirus treatments focusing on killing the virus or on preventing infection using vaccines largely ignore the host immune response. The relatively small body of current research on the virus indicates pathological responses by the immune system as the leading cause for much of the morbidity and mortality caused by COVID-19. In this review, we investigated the host innate and adaptive immune responses against COVID-19, collated information on recent COVID-19 experimental data, and summarized the systemic immune responses to and histopathology of SARS-CoV-2 infection. Finally, we summarized the immune-related biomarkers to define patients with high-risk and worst-case outcomes, and identified the possible usefulness of inflammatory markers as potential immunotherapeutic targets. This review provides an overview of current knowledge on COVID-19 and the symptomatological differences between healthy, convalescent, and severe cohorts, while offering research directions for alternative immunoregulation therapeutic targets. |Adaptive Immunity/*physiology[MESH] |Biomarkers[MESH] |Humans[MESH] |Immunity, Innate/*physiology[MESH]Role of the Immune Microenvironment in SARS-CoV-2 Infection (epmc).pdf DeepDyve Pubget Overpricing