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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Int+J+Infect+Dis 2021 ; 107 (ä): 201-204 Nephropedia Template TP
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Performance of SARS-CoV-2 rapid antigen test compared with real-time RT-PCR in asymptomatic individuals #MMPMID33945868
Pena M; Ampuero M; Garces C; Gaggero A; Garcia P; Velasquez MS; Luza R; Alvarez P; Paredes F; Acevedo J; Farfan MJ; Solari S; Soto-Rifo R; Valiente-Echeverria F
Int J Infect Dis 2021[Jun]; 107 (ä): 201-204 PMID33945868show ga
Screening, testing and contact tracing plays a pivotal role in control of the COVID-19 pandemic. To enable this it is necessary to increase the testing capacity. This study compared a SARS-CoV-2 rapid antigen test (RAT) and RT-PCR in 842 asymptomatic individuals from Tarapaca, Chile. A sensitivity of 69.86%, specificity of 99.61%, PPV of 94.44% and NPP of 97.22% with Ct values (Ct > 27) that were significantly higher among individuals with false-negative RAT were reported. These results support the fact that RAT might have a significant impact on the identification of asymptomatic carriers in areas that lack suitable laboratories to perform SARS-CoV-2 real-time RT-PCR diagnostics, or the results take more than 24-48 h, as well as zones with high traffic of individuals such as border/customs, airports, interregional bus, train stations or in any mass testing campaign requiring rapid results.