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10.1002/adbi.202000624 http://scihub22266oqcxt.onion/10.1002/adbi.202000624 33943040!8212094!33943040     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33943040&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Adv+Biol+(Weinh) 2021 ; 5 (6): e2000624 Nephropedia Template TP {{tp|p=33943040|t=2021. In Vitro Models for Studying Respiratory Host-Pathogen Interactions |pdf=|usr=}}{{33943040}} gab.com Text In Vitro Models for Studying Respiratory Host-Pathogen Interactions JO: Adv Biol (Weinh) http://www.kidney.de/pget.php?&tw=1&pmid=33943040 #FOAvip Respiratory diseases and lower respiratory tract infections are among the leading cause of death worldwide and, especially given the recent severe acute respiratory syndrome coronavirus-2 pandemic, are of high and prevalent socio-economic importance. In vitro models, which accurately represent the lung microenvironment, are of increasing significance given the ethical concerns around animal work and the lack of translation to human disease, as well as the lengthy time to market and the attrition rates associated with clinical trials. This review gives an overview of the biological and immunological components involved in regulating the respiratory epithelium system in health, disease, and infection. The evolution from 2D to 3D cell biology and to more advanced technological integrated models for studying respiratory host-pathogen interactions are reviewed and provide a reference point for understanding the in vitro modeling requirements. Finally, the current limitations and future perspectives for advancing this field are presented. Twit Text FOAVip In Vitro Models for Studying Respiratory Host-Pathogen Interactions ????Adv Biol (Weinh) http://www.kidney.de/pget.php?&tw=1&pmid=33943040 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33943040 #FOAvip English Wikipedia <ref>{{Cite pmid|33943040}}</ref> In Vitro Models for Studying Respiratory Host-Pathogen Interactions #MMPMID33943040 Barron SL; Saez J; Owens RM Adv Biol (Weinh) 2021[Jun]; 5 (6): e2000624 PMID33943040show ga Respiratory diseases and lower respiratory tract infections are among the leading cause of death worldwide and, especially given the recent severe acute respiratory syndrome coronavirus-2 pandemic, are of high and prevalent socio-economic importance. In vitro models, which accurately represent the lung microenvironment, are of increasing significance given the ethical concerns around animal work and the lack of translation to human disease, as well as the lengthy time to market and the attrition rates associated with clinical trials. This review gives an overview of the biological and immunological components involved in regulating the respiratory epithelium system in health, disease, and infection. The evolution from 2D to 3D cell biology and to more advanced technological integrated models for studying respiratory host-pathogen interactions are reviewed and provide a reference point for understanding the in vitro modeling requirements. Finally, the current limitations and future perspectives for advancing this field are presented. |*Models, Biological[MESH] |Animals[MESH] |COVID-19/*metabolism[MESH] |Host-Pathogen Interactions/*physiology[MESH] |Humans[MESH]In Vitro Models for Studying Respiratory Host-Pathogen Interactions (epmc).pdf DeepDyve Pubget Overpricing