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10.1186/s40035-021-00237-2 http://scihub22266oqcxt.onion/10.1186/s40035-021-00237-2 33941272!8090526!33941272     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Transl+Neurodegener 2021 ; 10 (1): 15 Nephropedia Template TP {{tp|p=33941272|t=2021. COVID-19 and Alzheimer s disease: how one crisis worsens the other |pdf=|usr=}}{{33941272}} gab.com Text COVID-19 and Alzheimer s disease: how one crisis worsens the other JO: Transl Neurodegener http://www.kidney.de/pget.php?&tw=1&pmid=33941272 #FOAvip Alzheimer's disease (AD) has emerged as a key comorbidity of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The morbidity and mortality of COVID-19 are elevated in AD due to multiple pathological changes in AD patients such as the excessive expression of viral receptor angiotensin converting enzyme 2 and pro-inflammatory molecules, various AD complications including diabetes, lifestyle alterations in AD, and drug-drug interactions. Meanwhile, COVID-19 has also been reported to cause various neurologic symptoms including cognitive impairment that may ultimately result in AD, probably through the invasion of SARS-CoV-2 into the central nervous system, COVID-19-induced inflammation, long-term hospitalization and delirium, and post-COVID-19 syndrome. In addition, the COVID-19 crisis also worsens behavioral symptoms in uninfected AD patients and poses new challenges for AD prevention. In this review, we first introduce the symptoms and pathogenesis of COVID-19 and AD. Next, we provide a comprehensive discussion on the aggravating effects of AD on COVID-19 and the underlying mechanisms from molecular to social levels. We also highlight the influence of COVID-19 on cognitive function, and propose possible routes of viral invasion into the brain and potential mechanisms underlying the COVID-19-induced cognitive impairment. Last, we summarize the negative impacts of COVID-19 pandemic on uninfected AD patients and dementia prevention. Twit Text FOAVip COVID-19 and Alzheimer s disease: how one crisis worsens the other ????Transl Neurodegener http://www.kidney.de/pget.php?&tw=1&pmid=33941272 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33941272 #FOAvip English Wikipedia <ref>{{Cite pmid|33941272}}</ref> COVID-19 and Alzheimer s disease: how one crisis worsens the other #MMPMID33941272 Xia X; Wang Y; Zheng J Transl Neurodegener 2021[Apr]; 10 (1): 15 PMID33941272show ga Alzheimer's disease (AD) has emerged as a key comorbidity of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The morbidity and mortality of COVID-19 are elevated in AD due to multiple pathological changes in AD patients such as the excessive expression of viral receptor angiotensin converting enzyme 2 and pro-inflammatory molecules, various AD complications including diabetes, lifestyle alterations in AD, and drug-drug interactions. Meanwhile, COVID-19 has also been reported to cause various neurologic symptoms including cognitive impairment that may ultimately result in AD, probably through the invasion of SARS-CoV-2 into the central nervous system, COVID-19-induced inflammation, long-term hospitalization and delirium, and post-COVID-19 syndrome. In addition, the COVID-19 crisis also worsens behavioral symptoms in uninfected AD patients and poses new challenges for AD prevention. In this review, we first introduce the symptoms and pathogenesis of COVID-19 and AD. Next, we provide a comprehensive discussion on the aggravating effects of AD on COVID-19 and the underlying mechanisms from molecular to social levels. We also highlight the influence of COVID-19 on cognitive function, and propose possible routes of viral invasion into the brain and potential mechanisms underlying the COVID-19-induced cognitive impairment. Last, we summarize the negative impacts of COVID-19 pandemic on uninfected AD patients and dementia prevention. |*Pandemics[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Alzheimer Disease/*complications/epidemiology[MESH] |COVID-19/*complications/epidemiology[MESH] |Comorbidity[MESH]COVID-19 and Alzheimer s disease: how one crisis worsens the other (epmc).pdf DeepDyve Pubget Overpricing