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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Clin+Gastroenterol+Hepatol 2021 ; 19 (9): 1970-1972.e3 Nephropedia Template TP
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Hepatobiliary Adverse Drug Reactions Associated With Remdesivir: The WHO International Pharmacovigilance Study #MMPMID33940227
Kim MS; Jung SY; Lee SW; Li H; Koyanagi A; Kronbichler A; Dragioti E; Tizaoui K; Wasuwanich P; Hong SH; Ghayda RA; Yoo HW; Kim H; Jacob L; Salem JE; Kostev K; Shin YH; Kim SY; Gamerith G; Yon DK; Shin JI; Smith L
Clin Gastroenterol Hepatol 2021[Sep]; 19 (9): 1970-1972.e3 PMID33940227show ga
Remdesivir has demonstrated clinical benefits in randomized placebo-controlled trials (RCTs) in patients with coronavirus disease 2019 (COVID-19)(1-4) and was first approved for COVID-19 patients.(5) However, whether remdesivir causes gastrointestinal adverse drug reaction (GI-ADRs) including hepatotoxicity is less clear.(1-4)(,)(6) Therefore, we aimed to detect a diverse spectrum of GI-ADRs associated with remdesivir using VigiBase, the World Health Organization's international pharmacovigilance database of individual case safety reports.
|*COVID-19 Drug Treatment[MESH]
|*Drug-Related Side Effects and Adverse Reactions/epidemiology[MESH]