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10.1016/j.cgh.2021.04.039

http://scihub22266oqcxt.onion/10.1016/j.cgh.2021.04.039
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33940227!ä!33940227

suck abstract from ncbi


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pmid33940227      Clin+Gastroenterol+Hepatol 2021 ; 19 (9): 1970-1972.e3
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  • Hepatobiliary Adverse Drug Reactions Associated With Remdesivir: The WHO International Pharmacovigilance Study #MMPMID33940227
  • Kim MS; Jung SY; Lee SW; Li H; Koyanagi A; Kronbichler A; Dragioti E; Tizaoui K; Wasuwanich P; Hong SH; Ghayda RA; Yoo HW; Kim H; Jacob L; Salem JE; Kostev K; Shin YH; Kim SY; Gamerith G; Yon DK; Shin JI; Smith L
  • Clin Gastroenterol Hepatol 2021[Sep]; 19 (9): 1970-1972.e3 PMID33940227show ga
  • Remdesivir has demonstrated clinical benefits in randomized placebo-controlled trials (RCTs) in patients with coronavirus disease 2019 (COVID-19)(1-4) and was first approved for COVID-19 patients.(5) However, whether remdesivir causes gastrointestinal adverse drug reaction (GI-ADRs) including hepatotoxicity is less clear.(1-4)(,)(6) Therefore, we aimed to detect a diverse spectrum of GI-ADRs associated with remdesivir using VigiBase, the World Health Organization's international pharmacovigilance database of individual case safety reports.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Drug-Related Side Effects and Adverse Reactions/epidemiology[MESH]
  • |Adenosine Monophosphate/analogs & derivatives[MESH]
  • |Adverse Drug Reaction Reporting Systems[MESH]
  • |Alanine/analogs & derivatives[MESH]
  • |Databases, Factual[MESH]
  • |Humans[MESH]
  • |Pharmacovigilance[MESH]
  • |SARS-CoV-2[MESH]


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