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10.1016/j.rvsc.2021.04.024 http://scihub22266oqcxt.onion/10.1016/j.rvsc.2021.04.024 33932822!8061179!33932822     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Res+Vet+Sci 2021 ; 137 (ä): 44-47 Nephropedia Template TP {{tp|p=33932822|t=2021. Virucidal and antiviral effects of Thymus vulgaris essential oil on feline coronavirus |pdf=|usr=}}{{33932822}} gab.com Text Virucidal and antiviral effects of Thymus vulgaris essential oil on feline coronavirus JO: Res Vet Sci http://www.kidney.de/pget.php?&tw=1&pmid=33932822 #FOAvip Feline infectious peritonitis (FIP) is a fatal systemic disease of felids caused by a Coronavirus (CoV) (FIPV). In spite of its clinical relevance and impact on feline health, currently the therapeutic possibilities for treatment of FIP in cats are limited. The emergence of the pandemic Severe Respiratory Syndrome (SARS) coronavirus (CoV) type 2 (SARS-CoV-2), etiological agent of the 2019 Coronavirus Disease (COVID-19), able to infect a broad spectrum of animal species including cats, triggered the interest for the development of novel molecules with antiviral activity for treatment of CoV infections in humans and animals. Essential oils (EOs) have raised significant attention for their antiviral properties integrating and, in some cases, replacing conventional drugs. Thymus vulgaris EO (TEO) has been previously shown to be effective against several RNA viruses including CoVs. In the present study the antiviral efficacy of TEO against FIPV was evaluated in vitro. TEO at 27 mug/ml was able to inhibit virus replication with a significant reduction of 2 log10 TCID(50)/50 mul. Moreover, virucidal activity was tested using TEO at 27 and 270 mug/ml, over the cytotoxic threshold, determining a reduction of viral titre as high as 3.25 log10 TCID(50)/50 mul up to 1 h of time contact. These results open several perspectives in terms of future applications and therapeutic possibilities for coronaviruses considering that FIPV infection in cats could be a potential model for the study of antivirals against CoVs. Twit Text FOAVip Virucidal and antiviral effects of Thymus vulgaris essential oil on feline coronavirus ????Res Vet Sci http://www.kidney.de/pget.php?&tw=1&pmid=33932822 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33932822 #FOAvip English Wikipedia <ref>{{Cite pmid|33932822}}</ref> Virucidal and antiviral effects of Thymus vulgaris essential oil on feline coronavirus #MMPMID33932822 Catella C; Camero M; Lucente MS; Fracchiolla G; Sblano S; Tempesta M; Martella V; Buonavoglia C; Lanave G Res Vet Sci 2021[Jul]; 137 (ä): 44-47 PMID33932822show ga Feline infectious peritonitis (FIP) is a fatal systemic disease of felids caused by a Coronavirus (CoV) (FIPV). In spite of its clinical relevance and impact on feline health, currently the therapeutic possibilities for treatment of FIP in cats are limited. The emergence of the pandemic Severe Respiratory Syndrome (SARS) coronavirus (CoV) type 2 (SARS-CoV-2), etiological agent of the 2019 Coronavirus Disease (COVID-19), able to infect a broad spectrum of animal species including cats, triggered the interest for the development of novel molecules with antiviral activity for treatment of CoV infections in humans and animals. Essential oils (EOs) have raised significant attention for their antiviral properties integrating and, in some cases, replacing conventional drugs. Thymus vulgaris EO (TEO) has been previously shown to be effective against several RNA viruses including CoVs. In the present study the antiviral efficacy of TEO against FIPV was evaluated in vitro. TEO at 27 mug/ml was able to inhibit virus replication with a significant reduction of 2 log10 TCID(50)/50 mul. Moreover, virucidal activity was tested using TEO at 27 and 270 mug/ml, over the cytotoxic threshold, determining a reduction of viral titre as high as 3.25 log10 TCID(50)/50 mul up to 1 h of time contact. These results open several perspectives in terms of future applications and therapeutic possibilities for coronaviruses considering that FIPV infection in cats could be a potential model for the study of antivirals against CoVs. |Animals[MESH] |Cats[MESH] |Cell Line[MESH] |Coronavirus, Feline/*drug effects[MESH] |Humans[MESH] |Oils, Volatile/chemistry/*pharmacology[MESH] |Plant Oils/chemistry/*pharmacology[MESH] |Thymus Plant/*chemistry[MESH]Virucidal and antiviral effects of Thymus vulgaris essential oil on fe(epmc).pdf DeepDyve Pubget Overpricing