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10.1111/ijcp.14311

http://scihub22266oqcxt.onion/10.1111/ijcp.14311
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suck abstract from ncbi


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pmid33932309      Int+J+Clin+Pract 2021 ; 75 (8): e14311
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  • Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is influenced by the type of transport medium: Implications for diagnosis and monitoring #MMPMID33932309
  • Patkar N; Rajpal S; Shetty N; Gokarn A; Mirgh S; Munipally S; Nair S; Joshi A; Murthy V; Khattry N; Gupta S
  • Int J Clin Pract 2021[Aug]; 75 (8): e14311 PMID33932309show ga
  • It is unclear if the use of a molecular transport medium (MTM) containing guanidine isothiocyanate (GITC) would be advantageous over the CDC recommended, commonly used viral transport medium (VTM). We retested 70 SARS-CoV2 cases by RT-PCR in varying stages of follow-up using MTM and VTM in parallel and found discrepant results of RNase P, E and N genes. Majority (81%) patients tested positive with MTM as compared with VTM (27.1%). Even patients who were sampled 3 weeks after diagnosis demonstrated a significant discrepancy in the positivity rates between MTM vs VTM raising concerns about the clinical utility of VTM.
  • |*COVID-19[MESH]
  • |*SARS-CoV-2[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques[MESH]
  • |Humans[MESH]


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