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10.1016/j.intimp.2021.107686

http://scihub22266oqcxt.onion/10.1016/j.intimp.2021.107686
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suck abstract from ncbi


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pmid33930705      Int+Immunopharmacol 2021 ; 97 (ä): 107686
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  • The role of vitamin D in reducing SARS-CoV-2 infection: An update #MMPMID33930705
  • Shah Alam M; Czajkowsky DM; Aminul Islam M; Ataur Rahman M
  • Int Immunopharmacol 2021[Aug]; 97 (ä): 107686 PMID33930705show ga
  • The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is having a disastrous impact on global health. Recently, several studies examined the potential of vitamin D to reduce the effects of SARS-CoV-2 infection by modulating the immune system. Indeed, vitamin D has been found to boost the innate immune system and stimulate the adaptive immune response against SARS-CoV-2 infection. In this review, we provide a comprehensive update of the immunological mechanisms underlying the positive effects of vitamin D in reducing SARS-CoV-2 infection as well as a thorough survey of the recent epidemiological studies and clinical trials that tested vitamin D as a potential therapeutic agent against COVID-19 infection. We believe that a better understanding of the histopathology and immunopathology of the disease as well as the mechanism of vitamin D effects on COVID-19 severity will ultimately pave the way for a more effective prevention and control of this global pandemic.
  • |Adaptive Immunity/drug effects[MESH]
  • |COVID-19/etiology/immunology/*prevention & control[MESH]
  • |Dietary Supplements[MESH]
  • |Humans[MESH]
  • |Immunity, Innate/drug effects[MESH]
  • |Seasons[MESH]
  • |Severity of Illness Index[MESH]


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