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10.1080/14760584.2021.1925112

http://scihub22266oqcxt.onion/10.1080/14760584.2021.1925112
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suck abstract from ncbi


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pmid33929930      Expert+Rev+Vaccines 2021 ; 20 (7): 891-898
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  • Safety of an inactivated SARS-CoV-2 vaccine among healthcare workers in China #MMPMID33929930
  • Zhang MX; Zhang TT; Shi GF; Cheng FM; Zheng YM; Tung TH; Chen HX
  • Expert Rev Vaccines 2021[Jul]; 20 (7): 891-898 PMID33929930show ga
  • Background: Although the inactivated SARS-CoV-2 vaccine (CoronaVac) has undergone preclinical tests and clinical trials evaluating its efficacy and safety, few data have been reported in the post-licensure real-world setting. We aimed to assess the safety of the vaccine among healthcare workers.Methods: A self-administered online survey on monitoring adverse reactions post vaccination was conducted among the staff who worked at and were vaccinated in a tertiary hospital in Taizhou, China, from February 24 to 7 March 2021. A total of 1526 subjects responded to the questionnaire when they received an e-mail or an e-poster on WeChat.Results: The incidences of overall adverse reactions after the first and second injections were 15.6% (238/1526) and 14.6% (204/1397), respectively. The most common adverse reaction was localized pain at the injection site, with an incidence of 9.6% and 10.7% after each dose, accounting for 61.8% and 73.0% of adverse reactions, respectively. Fatigue, muscle pain, and headache were the most common systemic adverse reactions.Conclusions: These findings implied that the inactivated CoronaVac vaccine has an acceptable safety profile among healthcare workers due to the low incidence of self-reported adverse reactions. This may boost public confidence in nationwide mass vaccination campaigns.
  • |*Health Personnel[MESH]
  • |*Self Report[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |COVID-19 Vaccines/*administration & dosage/adverse effects[MESH]
  • |COVID-19/epidemiology/*prevention & control[MESH]
  • |China/epidemiology[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Vaccines, Inactivated/*administration & dosage/adverse effects[MESH]


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