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10.1093/labmed/lmab033 http://scihub22266oqcxt.onion/10.1093/labmed/lmab033 33928384!8135470!33928384     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33928384&cmd=llinks): Failed to open stream: HTTP request failed! 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Utility of Antigen-Based Rapid Diagnostic Test for Detection of SARS-CoV-2 Virus in Routine Hospital Settings |pdf=|usr=}}{{33928384}} gab.com Text Utility of Antigen-Based Rapid Diagnostic Test for Detection of SARS-CoV-2 Virus in Routine Hospital Settings JO: Lab Med http://www.kidney.de/pget.php?&tw=1&pmid=33928384 #FOAvip OBJECTIVE: This study aims to evaluate the performance of an antigen-based rapid diagnostic test (RDT) for the detection of the SARS-CoV-2 virus. METHODS: A cross-sectional study was conducted on 677 patients. Two nasopharyngeal swabs and 1 oropharyngeal swab were collected from patients. The RDT was performed onsite by a commercially available immune-chromatographic assay on the nasopharyngeal swab. The nasopharyngeal and oropharyngeal swabs were examined for SARS-CoV-2 RNA by real-time reverse-transcription quantitative polymerase chain reaction (RT-qPCR) assay. RESULTS: The overall sensitivity of the SARS-CoV-2 RDT was 34.5% and the specificity was 99.8%. The positive predictive value and negative predictive value of the test were 96.6% and 91.5%, respectively. The detection rate of RDT in RT-qPCR positive results was high (45%) for cycle threshold values <25. CONCLUSION: The utility of RDT is in diagnosing symptomatic patients and may not be particularly suited as a screening tool for patients with low viral load. The low sensitivity of RDT does not qualify its use as a single test in patients who test negative; RT-qPCR continues to be the gold standard test. Twit Text FOAVip Utility of Antigen-Based Rapid Diagnostic Test for Detection of SARS-CoV-2 Virus in Routine Hospital Settings ????Lab Med http://www.kidney.de/pget.php?&tw=1&pmid=33928384 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33928384 #FOAvip English Wikipedia <ref>{{Cite pmid|33928384}}</ref> Utility of Antigen-Based Rapid Diagnostic Test for Detection of SARS-CoV-2 Virus in Routine Hospital Settings #MMPMID33928384 Thakur P; Saxena S; Manchanda V; Rana N; Goel R; Arora R Lab Med 2021[Nov]; 52 (6): e154-e158 PMID33928384show ga OBJECTIVE: This study aims to evaluate the performance of an antigen-based rapid diagnostic test (RDT) for the detection of the SARS-CoV-2 virus. METHODS: A cross-sectional study was conducted on 677 patients. Two nasopharyngeal swabs and 1 oropharyngeal swab were collected from patients. The RDT was performed onsite by a commercially available immune-chromatographic assay on the nasopharyngeal swab. The nasopharyngeal and oropharyngeal swabs were examined for SARS-CoV-2 RNA by real-time reverse-transcription quantitative polymerase chain reaction (RT-qPCR) assay. RESULTS: The overall sensitivity of the SARS-CoV-2 RDT was 34.5% and the specificity was 99.8%. The positive predictive value and negative predictive value of the test were 96.6% and 91.5%, respectively. The detection rate of RDT in RT-qPCR positive results was high (45%) for cycle threshold values <25. CONCLUSION: The utility of RDT is in diagnosing symptomatic patients and may not be particularly suited as a screening tool for patients with low viral load. The low sensitivity of RDT does not qualify its use as a single test in patients who test negative; RT-qPCR continues to be the gold standard test. |Adolescent[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Antigens, Viral/*genetics[MESH] |Automation, Laboratory[MESH] |COVID-19 Serological Testing/methods/*standards[MESH] |COVID-19/*diagnosis/immunology/virology[MESH] |Chromatography, Affinity/*methods[MESH] |Cross-Sectional Studies[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Nasopharynx/virology[MESH] |Oropharynx/virology[MESH] |RNA, Viral/*genetics[MESH] |Reagent Kits, Diagnostic[MESH] |Reverse Transcriptase Polymerase Chain Reaction/methods[MESH] |SARS-CoV-2/*genetics/immunology[MESH] |Sensitivity and Specificity[MESH]Utility of Antigen-Based Rapid Diagnostic Test for Detection of SARS-C(epmc).pdf DeepDyve Pubget Overpricing