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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Arch+Cardiovasc+Dis 2021 ; 114 (5): 340-351 Nephropedia Template TP
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ST-segment elevation myocardial infarction: Management and association with prognosis during the COVID-19 pandemic in France #MMPMID33926830
Bonnet G; Panagides V; Becker M; Riviere N; Yvorel C; Deney A; Lattuca B; Duband B; Moussa K; Juenin L; Pamart T; Semaan C; Uhry S; Noirclerc N; Vincent F; Vignac M; Palermo V; Martin AS; Zeitouni M; Van Belle E; Tirouvanziam A; Manchuelle A; Chamandi C; Kerneis M; Boukantar M; Belle L; De Poli F; Angoulvant D; Meneveau N; Robin M; Pansieri M; Bonello L; Motreff P; Bouisset F; Isaaz K; Cetran L; Khalife K; Lesizza P; Adjedj J; Benamer H; Cayla G
Arch Cardiovasc Dis 2021[May]; 114 (5): 340-351 PMID33926830show ga
BACKGROUND: Systems of care have been challenged to control progression of the COVID-19 pandemic. Whether this has been associated with delayed reperfusion and worse outcomes in French patients with ST-segment elevation myocardial infarction (STEMI) is unknown. AIM: To compare the rate of STEMI admissions, treatment delays, and outcomes between the first peak of the COVID-19 pandemic in France and the equivalent period in 2019. METHODS: In this nationwide French survey, data from consecutive STEMI patients from 65 centres referred for urgent revascularization between 1 March and 31 May 2020, and between 1 March and 31 May 2019, were analysed. The primary outcome was a composite of in-hospital death or non-fatal mechanical complications of acute myocardial infarction. RESULTS: A total of 6306 patients were included. During the pandemic peak, a 13.9+/-6.6% (P=0.003) decrease in STEMI admissions per week was observed. Delays between symptom onset and percutaneous coronary intervention were longer in 2020 versus 2019 (270 [interquartile range 150-705] vs 245 [140-646]min; P=0.013), driven by the increase in time from symptom onset to first medical contact (121 [60-360] vs 150 [62-420]min; P=0.002). During 2020, a greater number of mechanical complications was observed (0.9% vs 1.7%; P=0.029) leading to a significant difference in the primary outcome (112 patients [5.6%] in 2019 vs 129 [7.6%] in 2020; P=0.018). No significant difference was observed in rates of orotracheal intubation, in-hospital cardiac arrest, ventricular arrhythmias and cardiogenic shock. CONCLUSIONS: During the first peak of the COVID-19 pandemic in France, there was a decrease in STEMI admissions, associated with longer ischaemic time, exclusively driven by an increase in patient-related delays and an increase in mechanical complications. These findings suggest the need to encourage the population to seek medical help in case of symptoms.