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10.1016/j.acvd.2021.01.005

http://scihub22266oqcxt.onion/10.1016/j.acvd.2021.01.005
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suck abstract from ncbi


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pmid33926830      Arch+Cardiovasc+Dis 2021 ; 114 (5): 340-351
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  • ST-segment elevation myocardial infarction: Management and association with prognosis during the COVID-19 pandemic in France #MMPMID33926830
  • Bonnet G; Panagides V; Becker M; Riviere N; Yvorel C; Deney A; Lattuca B; Duband B; Moussa K; Juenin L; Pamart T; Semaan C; Uhry S; Noirclerc N; Vincent F; Vignac M; Palermo V; Martin AS; Zeitouni M; Van Belle E; Tirouvanziam A; Manchuelle A; Chamandi C; Kerneis M; Boukantar M; Belle L; De Poli F; Angoulvant D; Meneveau N; Robin M; Pansieri M; Bonello L; Motreff P; Bouisset F; Isaaz K; Cetran L; Khalife K; Lesizza P; Adjedj J; Benamer H; Cayla G
  • Arch Cardiovasc Dis 2021[May]; 114 (5): 340-351 PMID33926830show ga
  • BACKGROUND: Systems of care have been challenged to control progression of the COVID-19 pandemic. Whether this has been associated with delayed reperfusion and worse outcomes in French patients with ST-segment elevation myocardial infarction (STEMI) is unknown. AIM: To compare the rate of STEMI admissions, treatment delays, and outcomes between the first peak of the COVID-19 pandemic in France and the equivalent period in 2019. METHODS: In this nationwide French survey, data from consecutive STEMI patients from 65 centres referred for urgent revascularization between 1 March and 31 May 2020, and between 1 March and 31 May 2019, were analysed. The primary outcome was a composite of in-hospital death or non-fatal mechanical complications of acute myocardial infarction. RESULTS: A total of 6306 patients were included. During the pandemic peak, a 13.9+/-6.6% (P=0.003) decrease in STEMI admissions per week was observed. Delays between symptom onset and percutaneous coronary intervention were longer in 2020 versus 2019 (270 [interquartile range 150-705] vs 245 [140-646]min; P=0.013), driven by the increase in time from symptom onset to first medical contact (121 [60-360] vs 150 [62-420]min; P=0.002). During 2020, a greater number of mechanical complications was observed (0.9% vs 1.7%; P=0.029) leading to a significant difference in the primary outcome (112 patients [5.6%] in 2019 vs 129 [7.6%] in 2020; P=0.018). No significant difference was observed in rates of orotracheal intubation, in-hospital cardiac arrest, ventricular arrhythmias and cardiogenic shock. CONCLUSIONS: During the first peak of the COVID-19 pandemic in France, there was a decrease in STEMI admissions, associated with longer ischaemic time, exclusively driven by an increase in patient-related delays and an increase in mechanical complications. These findings suggest the need to encourage the population to seek medical help in case of symptoms.
  • |*Pandemics[MESH]
  • |COVID-19/*epidemiology[MESH]
  • |Comorbidity[MESH]
  • |Diabetes Mellitus/epidemiology[MESH]
  • |Female[MESH]
  • |France/epidemiology[MESH]
  • |Health Care Surveys[MESH]
  • |Heart Rupture, Post-Infarction/epidemiology[MESH]
  • |Hospital Mortality[MESH]
  • |Humans[MESH]
  • |Hyperlipidemias/epidemiology[MESH]
  • |Hypertension/epidemiology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Patient Acceptance of Health Care[MESH]
  • |Patient Admission/statistics & numerical data[MESH]
  • |Percutaneous Coronary Intervention/statistics & numerical data[MESH]
  • |Procedures and Techniques Utilization[MESH]
  • |Prognosis[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]
  • |ST Elevation Myocardial Infarction/complications/epidemiology/*therapy[MESH]
  • |Smoking/epidemiology[MESH]
  • |Stents[MESH]
  • |Time-to-Treatment[MESH]


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