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Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Pancreatology 2021 ; 21 (6): 1048-51 Nephropedia Template TP
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COVID-19 related pancreatic cancer surveillance disruptions amongst high-risk individuals #MMPMID33926820
Katona BW; Mahmud N; Dbouk M; Ahmad N; Chhoda A; Dudley B; Hayat U; Kwon RS; Lee LS; Rustgi AK; Ukaegbu C; Vasquez L; Volk S; Brand RE; Canto MI; Chak A; Farrell JJ; Kastrinos F; Stoffel EM; Syngal S; Goggins M
Pancreatology 2021[Apr]; 21 (6): 1048-51 PMID33926820show ga
BACKGROUND: COVID-19 pandemic-related disruptions to EUS-based pancreatic cancer surveillance in high-risk individuals remain uncertain. METHODS: Analysis of enrolled participants in the CAPS5 Study, a prospective multicenter study of pancreatic cancer surveillance in high-risk individuals. RESULTS: Amongst 693 enrolled high-risk individuals under active surveillance, 108 (16%) had an EUS scheduled during the COVID-19 pandemic-related shutdown (median length of 78 days) in the spring of 2020, with 97% of these procedures being canceled. Of these canceled surveillance EUSs, 83% were rescheduled in a median of 4.1 months, however 17% were not rescheduled after 6 months follow-up. Prior history of cancer was associated with increased likelihood of rescheduling. To date no pancreatic cancer has been diagnosed among those whose surveillance was delayed. CONCLUSIONS: COVID-19 delayed pancreatic cancer surveillance with no adverse outcomes in efficiently rescheduled individuals. However, 1 in 6 high-risk individuals had not rescheduled surveillance, indicating the need for vigilance to ensure timely surveillance rescheduling.