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10.3390/jcm10081580 http://scihub22266oqcxt.onion/10.3390/jcm10081580 33918081!8070215!33918081     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Clin+Med 2021 ; 10 (8): ä Nephropedia Template TP {{tp|p=33918081|t=2021. Evaluation of a Broad Panel of SARS-CoV-2 Serological Tests for Diagnostic Use |pdf=|usr=}}{{33918081}} gab.com Text Evaluation of a Broad Panel of SARS-CoV-2 Serological Tests for Diagnostic Use JO: J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=33918081 #FOAvip Serological testing is crucial in detection of previous infection and in monitoring convalescent and vaccine-induced immunity. During the Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) pandemic, numerous assay platforms have been developed and marketed for clinical use. Several studies recently compared clinical performance of a limited number of serological tests, but broad comparative evaluation is currently missing. Within this study, a panel of 161 sera from SARS-CoV-2 infected, seasonal CoV-infected and SARS-CoV-2 naive subjects was enrolled to evaluate 16 ELISA/ECLIA-based and 16 LFA-based tests. Specificities of all ELISA/ECLIA-based assays were acceptable and generally in agreement with the providers' specifications, but sensitivities were lower as specified. Results of the LFAs were less accurate as compared to the ELISAs, albeit with some exceptions. We found a sporadic unequal immune response for different antigens and thus recommend the use of a nucleocapsid protein (N)- and spike protein (S)-based test combination when maximal sensitivity is necessary. Finally, the quality of the immune response in terms of neutralization should be tested using S-based IgG tests. Twit Text FOAVip Evaluation of a Broad Panel of SARS-CoV-2 Serological Tests for Diagnostic Use ????J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=33918081 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33918081 #FOAvip English Wikipedia <ref>{{Cite pmid|33918081}}</ref> Evaluation of a Broad Panel of SARS-CoV-2 Serological Tests for Diagnostic Use #MMPMID33918081 Werner M; Pervan P; Gluck V; Zeman F; Koller M; Burkhardt R; Gluck T; Wenzel JJ; Schmidt B; Gessner A; Peterhoff D J Clin Med 2021[Apr]; 10 (8): ä PMID33918081show ga Serological testing is crucial in detection of previous infection and in monitoring convalescent and vaccine-induced immunity. During the Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) pandemic, numerous assay platforms have been developed and marketed for clinical use. Several studies recently compared clinical performance of a limited number of serological tests, but broad comparative evaluation is currently missing. Within this study, a panel of 161 sera from SARS-CoV-2 infected, seasonal CoV-infected and SARS-CoV-2 naive subjects was enrolled to evaluate 16 ELISA/ECLIA-based and 16 LFA-based tests. Specificities of all ELISA/ECLIA-based assays were acceptable and generally in agreement with the providers' specifications, but sensitivities were lower as specified. Results of the LFAs were less accurate as compared to the ELISAs, albeit with some exceptions. We found a sporadic unequal immune response for different antigens and thus recommend the use of a nucleocapsid protein (N)- and spike protein (S)-based test combination when maximal sensitivity is necessary. Finally, the quality of the immune response in terms of neutralization should be tested using S-based IgG tests. äEvaluation of a Broad Panel of SARS-CoV-2 Serological Tests for Diagno(epmc).pdf DeepDyve Pubget Overpricing