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10.3390/medicina57040363

http://scihub22266oqcxt.onion/10.3390/medicina57040363
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33917858!8068236!33917858
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suck abstract from ncbi


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pmid33917858      Medicina+(Kaunas) 2021 ; 57 (4): ä
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  • Population-Based COVID-19 Screening in Mexico: Assessment of Symptoms and Their Weighting in Predicting SARS-CoV-2 Infection #MMPMID33917858
  • Martinez-Fierro ML; Diaz-Lozano M; Alvarez-Zuniga C; Ramirez-Hernandez LA; Araujo-Espino R; Trejo-Ortiz PM; Mollinedo-Montano FE; Ortiz-Castro Y; Vazquez-Reyes S; Velasco-Elizondo P; Garcia-Esquivel L; Araujo-Conejo A; Garza-Veloz I
  • Medicina (Kaunas) 2021[Apr]; 57 (4): ä PMID33917858show ga
  • Background and Objectives: Sentinel surveillance in the early stage of the COVID-19 pandemic in Mexico represented a significant cost reduction and was useful in estimating the population infected with SARS-CoV-2. However, it also implied that many patients were not screened and therefore had no accurate diagnosis. In this study, we carried out a population-based SARS-CoV-2 screening in Mexico to evaluate the COVID-19-related symptoms and their weighting in predicting SARS-CoV-2 infection. We also discuss this data in the context of the operational definition of suspected cases of COVID-19 established by the Mexican Health Authority's consensus. Materials and Methods: One thousand two hundred seventy-nine subjects were included. They were screened for SARS-CoV-2 using RT-PCR. The weighting of COVID-19 symptoms in predicting SARS-CoV-2 infection was evaluated statistically. Results: Three hundred and twenty-five patients were positive for SARS-CoV-2 and 954 were negative. Fever, asthenia, dysgeusia, and oxygen saturation predicted SARS-CoV-2 infection (odds ratios ranged from 1.74 to 4.98; p < 0.05). The percentage of asymptomatic COVID-19 patients was 36% and only 38.15% met the Mexican operational definition. Cq-values for the gene N of SARS-CoV-2 were significantly higher in asymptomatic subjects than in the groups of COVID-19 patients with neurological, respiratory, and/or musculoskeletal manifestations (p < 0.05). Conclusions: Dysgeusia, fever, and asthenia increased the odds of a positive result for COVID-19 1.74-4.98-fold among the study population. Patients with neurological, respiratory, and/or musculoskeletal manifestations had higher viral loads at COVID-19 diagnosis than those observed in asymptomatic patients. A high percentage of the participants in the study (61.85%) did not meet the operational definition for a suspected case of COVID-19 established by the Mexican Health Authority's consensus, representing a high percentage of the population that could have remained without a COVID-19 diagnosis, so becoming a potential source of virus spread.
  • |*COVID-19[MESH]
  • |*Pandemics[MESH]
  • |COVID-19 Testing[MESH]
  • |Humans[MESH]
  • |Mexico/epidemiology[MESH]


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