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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Biomol+NMR+Assign 2021 ; 15 (2): 341-345 Nephropedia Template TP
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The (1)H, (15)N, and (13)C resonance assignments of the N-terminal domain of the nucleocapsid protein from the Middle East respiratory syndrome coronavirus #MMPMID33914244
de Araujo TS; Barbosa GM; Sanches K; Azevedo JM; Dos Santos Cabral KM; Almeida MS; Almeida FCL
Biomol NMR Assign 2021[Oct]; 15 (2): 341-345 PMID33914244show ga
During the past 17 years, the coronaviruses have become a global public emergency, with the first appearance in 2012 in Saudi Arabia of the Middle East respiratory syndrome. Among the structural proteins encoded in the viral genome, the nucleocapsid protein is the most abundant in infected cells. It is a multifunctional phosphoprotein involved in the capsid formation, in the modulation and regulation of the viral life cycle. The N-terminal domain of N protein specifically interacts with transcriptional regulatory sequence (TRS) and is involved in the discontinuous transcription through the melting activity of double-stranded TRS (dsTRS).
|*Middle East Respiratory Syndrome Coronavirus[MESH]