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10.1002/jmv.27037

http://scihub22266oqcxt.onion/10.1002/jmv.27037
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33913544!8242373!33913544
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suck abstract from ncbi


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pmid33913544      J+Med+Virol 2021 ; 93 (9): 5608-5613
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  • Characterization of T lymphocytes in severe COVID-19 patients #MMPMID33913544
  • Fenoglio D; Dentone C; Parodi A; Di Biagio A; Bozzano F; Vena A; Fabbi M; Ferrera F; Altosole T; Bruzzone B; Giacomini M; Pelosi P; De Maria A; Bassetti M; De Palma R; Filaci G
  • J Med Virol 2021[Sep]; 93 (9): 5608-5613 PMID33913544show ga
  • In this observational study, 13 patients with severe COVID-19 and 10 healthy controls were enrolled. The data concerning the analysis of circulating T cells show that, in severe COVID-19 patients, the expansion of these cell compartments is prone to induce antibody response, inflammation (CCR4+ and CCR6+ TFH) and regulation (CD8+ Treg). This pathogenic mechanism could lead us to envision a possible new form of biological target therapy.
  • |Adaptive Immunity[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Antibodies, Viral/*biosynthesis/immunology[MESH]
  • |CD4-Positive T-Lymphocytes/immunology[MESH]
  • |CD8-Positive T-Lymphocytes/*immunology[MESH]
  • |COVID-19/*immunology[MESH]
  • |Case-Control Studies[MESH]
  • |Female[MESH]
  • |Fluorescent Antibody Technique[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Receptors, CCR4[MESH]
  • |Receptors, CCR6[MESH]


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