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10.3389/fmolb.2021.647508

http://scihub22266oqcxt.onion/10.3389/fmolb.2021.647508
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suck abstract from ncbi


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pmid33912590      Front+Mol+Biosci 2021 ; 8 (ä): 647508
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  • Gastrointestinal Microenvironment and the Gut-Lung Axis in the Immune Responses of Severe COVID-19 #MMPMID33912590
  • Yang Y; Huang W; Fan Y; Chen GQ
  • Front Mol Biosci 2021[]; 8 (ä): 647508 PMID33912590show ga
  • The global pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an unprecedented threat to the human health. A close association of the digestive tract is implied by the high frequency of gastrointestinal syndromes among COVID-19 patients. A better understanding of the role of intestinal microenvironment in COVID-19 immunopathology will be helpful to improve the control of COVID-19 associated morbidity and mortality. This review summarizes the immune responses associated with the severity of COVID-19, the current evidence of SARS-CoV-2 intestinal tropism, and the potential involvement of gut microenvironment in COVID-19 severity. Additionally, we discuss the therapeutic potential of probiotics as an alternative medicine to prevent or alleviate severe COVID-19 outcome.
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