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10.1093/cid/ciab310 http://scihub22266oqcxt.onion/10.1093/cid/ciab310 33909063!8135387!33909063     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33909063&cmd=llinks): Failed to open stream: HTTP request failed! 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A Comparison of Less Invasive Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Diagnostic Specimens in Nursing Home Residents-Arkansas, June-August 2020 |pdf=|usr=}}{{33909063}} gab.com Text A Comparison of Less Invasive Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Diagnostic Specimens in Nursing Home Residents-Arkansas, June-August 2020 JO: Clin Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=33909063 #FOAvip BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing remains essential for early identification and clinical management of cases. We compared the diagnostic performance of 3 specimen types for characterizing SARS-CoV-2 in infected nursing home residents. METHODS: A convenience sample of 17 residents were enrolled within 15 days of first positive SARS-CoV-2 result by real-time reverse transcription polymerase chain reaction (RT-PCR) and prospectively followed for 42 days. Anterior nasal swabs (AN), oropharyngeal swabs (OP), and saliva specimens (SA) were collected on the day of enrollment, every 3 days for the first 21 days, and then weekly for 21 days. Specimens were tested for presence of SARS-CoV-2 RNA using RT-PCR and replication-competent virus by viral culture. RESULTS: Comparing the 3 specimen types collected from each participant at each time point, the concordance of paired RT-PCR results ranged from 80% to 88%. After the first positive result, SA and OP were RT-PCR-positive for </=48 days; AN were RT-PCR-positive for </=33 days. AN had the highest percentage of RT-PCR-positive results (21/26 [81%]) when collected </=10 days of participants' first positive result. Eleven specimens were positive by viral culture: 9 AN collected </=19 days following first positive result and 2 OP collected </=5 days following first positive result. CONCLUSIONS: AN, OP, and SA were effective methods for repeated testing in this population. More AN than OP were positive by viral culture. SA and OP remained RT-PCR-positive longer than AN, which could lead to unnecessary interventions if RT-PCR detection occurred after viral shedding has likely ceased. Twit Text FOAVip A Comparison of Less Invasive Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Diagnostic Specimens in Nursing Home Residents-Arkansas, June-August 2020 ????Clin Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=33909063 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33909063 #FOAvip English Wikipedia <ref>{{Cite pmid|33909063}}</ref> A Comparison of Less Invasive Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Diagnostic Specimens in Nursing Home Residents-Arkansas, June-August 2020 #MMPMID33909063 Gable P; Huang JY; Gilbert SE; Bollinger S; Lyons AK; Sabour S; Surie D; Biedron C; Haney T; Beshearse E; Gregory CJ; Seely KA; Clemmons NS; Patil N; Kothari A; Gulley T; Garner K; Anderson K; Thornburg NJ; Halpin AL; McDonald LC; Kutty PK; Brown AC Clin Infect Dis 2021[Jul]; 73 (Suppl 1): S58-S64 PMID33909063show ga BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing remains essential for early identification and clinical management of cases. We compared the diagnostic performance of 3 specimen types for characterizing SARS-CoV-2 in infected nursing home residents. METHODS: A convenience sample of 17 residents were enrolled within 15 days of first positive SARS-CoV-2 result by real-time reverse transcription polymerase chain reaction (RT-PCR) and prospectively followed for 42 days. Anterior nasal swabs (AN), oropharyngeal swabs (OP), and saliva specimens (SA) were collected on the day of enrollment, every 3 days for the first 21 days, and then weekly for 21 days. Specimens were tested for presence of SARS-CoV-2 RNA using RT-PCR and replication-competent virus by viral culture. RESULTS: Comparing the 3 specimen types collected from each participant at each time point, the concordance of paired RT-PCR results ranged from 80% to 88%. After the first positive result, SA and OP were RT-PCR-positive for |*COVID-19[MESH] |*SARS-CoV-2[MESH] |Arkansas[MESH] |Humans[MESH] |Nursing Homes[MESH]A Comparison of Less Invasive Severe Acute Respiratory Syndrome Corona(epmc).pdf DeepDyve Pubget Overpricing