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10.20529/IJME.2021.022 http://scihub22266oqcxt.onion/10.20529/IJME.2021.022 33908353!ä!33908353 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Indian+J+Med+Ethics 2021 ; VI (2): 1-7 Nephropedia Template TP {{tp|p=33908353|t=2021. Placebo control in Covid-19 trials: A missed opportunity for international guidance |pdf=|usr=}}{{33908353}} gab.com Text Placebo control in Covid-19 trials: A missed opportunity for international guidance JO: Indian J Med Ethics http://www.kidney.de/pget.php?&tw=1&pmid=33908353 #FOAvip Vaccines preventing Covid-19 have been approved in several countries. Is it still ethically acceptable to use placebo controls during the development of other vaccine options? If two of the most influential international guidelines of biomedical research are consulted, the Declaration of Helsinki and the CIOMS-guidelines, the answer is "no". We discuss the implications for ongoing vaccine research, and how placebo controls might be justified nevertheless. However, the ethical conflict remains highly problematic. We suggest that such ethical dilemmas should be avoided in the future by the introduction of a new system of global governance. Once vaccines are approved, a global regulation should oblige producers to provide the necessary amount of vaccine doses for the control groups of ongoing vaccine research. Twit Text FOAVip Placebo control in Covid-19 trials: A missed opportunity for international guidance ????Indian J Med Ethics http://www.kidney.de/pget.php?&tw=1&pmid=33908353 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33908353 #FOAvip English Wikipedia <ref>{{Cite pmid|33908353}}</ref> Placebo control in Covid-19 trials: A missed opportunity for international guidance #MMPMID33908353 Wiesing U; Ehni HJ Indian J Med Ethics 2021[Apr]; VI (2): 1-7 PMID33908353show ga Vaccines preventing Covid-19 have been approved in several countries. Is it still ethically acceptable to use placebo controls during the development of other vaccine options? If two of the most influential international guidelines of biomedical research are consulted, the Declaration of Helsinki and the CIOMS-guidelines, the answer is "no". We discuss the implications for ongoing vaccine research, and how placebo controls might be justified nevertheless. However, the ethical conflict remains highly problematic. We suggest that such ethical dilemmas should be avoided in the future by the introduction of a new system of global governance. Once vaccines are approved, a global regulation should oblige producers to provide the necessary amount of vaccine doses for the control groups of ongoing vaccine research. |*Ethics, Medical[MESH] |*Guidelines as Topic[MESH] |*International Cooperation[MESH] |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |COVID-19 Vaccines/*standards[MESH] |COVID-19/*prevention & control[MESH] |Clinical Trials as Topic/*standards[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Placebos/*standards[MESH]Placebo control in Covid-19 trials: A missed opportunity for internati(epmc).pdf DeepDyve Pubget Overpricing