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10.1038/s41598-021-88617-6 http://scihub22266oqcxt.onion/10.1038/s41598-021-88617-6 33903708!8076240!33903708     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33903708&cmd=llinks): Failed to open stream: HTTP request failed! 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The microRNA analysis portal is a next-generation tool for exploring and analyzing miRNA-focused data in the literature |pdf=|usr=}}{{33903708}} gab.com Text The microRNA analysis portal is a next-generation tool for exploring and analyzing miRNA-focused data in the literature JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33903708 #FOAvip MicroRNAs constitute a class of noncoding small RNAs involved in the posttranscriptional regulation of many biological pathways. In recent years, microRNAs have also been associated with regulation across kingdoms, demonstrating that exogenous miRNAs can function in mammals in a fashion similar to mammalian miRNAs. The growing interest in microRNAs and the increasing amount of literature and molecular and biomedical data available make it difficult to identify records of interest and keep up to date with novel findings. For these reasons, we developed the microRNA Analysis Portal (MAP). MAP selects relevant miRNA-focused articles from PubMed, links biomedical and molecular data and applies bioinformatics modules. At the time of this writing, MAP represents the richest, most complete and integrated database focused on microRNAs. MAP also integrates an updated version of MirCompare (2.0), a computational platform used for selecting plant microRNAs on the basis of their ability to regulate mammalian genes. Both MAP and MirCompare functionalities were used to predict that microRNAs from Moringa oleifera have putative roles across kingdoms by regulating human genes coding for proteins of the immune system. Starting from a selection of 94 human microRNAs, MirCompare selected 6 Moringa oleifera functional homologs. The subsequent prediction of human targets and areas of functional enrichment highlighted the central involvement of these genes in regulating immune system processes, particularly the host-virus interaction processes in hepatitis B, cytomegalovirus, papillomavirus and coronavirus. This case of use showed how MAP can help to perform complex queries without any computational background. MAP is available at http://stablab.uniroma2.it/MAP . Twit Text FOAVip The microRNA analysis portal is a next-generation tool for exploring and analyzing miRNA-focused data in the literature ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33903708 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33903708 #FOAvip English Wikipedia <ref>{{Cite pmid|33903708}}</ref> The microRNA analysis portal is a next-generation tool for exploring and analyzing miRNA-focused data in the literature #MMPMID33903708 Pirro S; Matic I; Colizzi V; Galgani A Sci Rep 2021[Apr]; 11 (1): 9007 PMID33903708show ga MicroRNAs constitute a class of noncoding small RNAs involved in the posttranscriptional regulation of many biological pathways. In recent years, microRNAs have also been associated with regulation across kingdoms, demonstrating that exogenous miRNAs can function in mammals in a fashion similar to mammalian miRNAs. The growing interest in microRNAs and the increasing amount of literature and molecular and biomedical data available make it difficult to identify records of interest and keep up to date with novel findings. For these reasons, we developed the microRNA Analysis Portal (MAP). MAP selects relevant miRNA-focused articles from PubMed, links biomedical and molecular data and applies bioinformatics modules. At the time of this writing, MAP represents the richest, most complete and integrated database focused on microRNAs. MAP also integrates an updated version of MirCompare (2.0), a computational platform used for selecting plant microRNAs on the basis of their ability to regulate mammalian genes. Both MAP and MirCompare functionalities were used to predict that microRNAs from Moringa oleifera have putative roles across kingdoms by regulating human genes coding for proteins of the immune system. Starting from a selection of 94 human microRNAs, MirCompare selected 6 Moringa oleifera functional homologs. The subsequent prediction of human targets and areas of functional enrichment highlighted the central involvement of these genes in regulating immune system processes, particularly the host-virus interaction processes in hepatitis B, cytomegalovirus, papillomavirus and coronavirus. This case of use showed how MAP can help to perform complex queries without any computational background. MAP is available at http://stablab.uniroma2.it/MAP . |Genes, Plant[MESH] |MicroRNAs/*genetics[MESH] |Moringa oleifera/genetics[MESH] |Principal Component Analysis[MESH]The microRNA analysis portal is a next-generation tool for exploring a(epmc).pdf DeepDyve Pubget Overpricing