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10.1128/JCM.00431-21 http://scihub22266oqcxt.onion/10.1128/JCM.00431-21 33903168!8218740!33903168     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Clin+Microbiol 2021 ; 59 (7): e0043121 Nephropedia Template TP {{tp|p=33903168|t=2021. SARS-CoV-2 Infection Detection by PCR and Serologic Testing in Clinical Practice |pdf=|usr=}}{{33903168}} gab.com Text SARS-CoV-2 Infection Detection by PCR and Serologic Testing in Clinical Practice JO: J Clin Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=33903168 #FOAvip Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be diagnosed by PCR during acute infection or later in their clinical course by detection of virus-specific antibodies. While in theory complementary, both PCR and serologic tests have practical shortcomings. A retrospective study was performed in order to further define these limitations in a clinical context and to determine how to best utilize these tests in a coherent fashion. A total of 3,075 patients underwent both PCR and serology tests at University of California, Los Angeles (UCLA), in the study period. Among these, 2,731 (89%) had no positive tests at all, 73 (2%) had a positive PCR test and only negative serology tests, 144 (5%) had a positive serology test and only negative PCR tests, and 127 (4%) had positive PCR and serology tests. Approximately half of the patients with discordant results (i.e., PCR positive and serology negative or vice versa) had mistimed tests in reference to the course of their disease. PCR-positive patients who were asymptomatic or pregnant were less likely to generate a detectable humoral immune response to SARS-CoV-2. On a quantitative level, the log number of days between symptom onset and PCR test was positively correlated with cycle threshold (C(T)) values. However, there was no apparent relationship between PCR C(T) and serologic (arbitrary units per milliliter) results. Twit Text FOAVip SARS-CoV-2 Infection Detection by PCR and Serologic Testing in Clinical Practice ????J Clin Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=33903168 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33903168 #FOAvip English Wikipedia <ref>{{Cite pmid|33903168}}</ref> SARS-CoV-2 Infection Detection by PCR and Serologic Testing in Clinical Practice #MMPMID33903168 Murad D; Chandrasekaran S; Pillai A; Garner OB; Denny CT J Clin Microbiol 2021[Jun]; 59 (7): e0043121 PMID33903168show ga Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be diagnosed by PCR during acute infection or later in their clinical course by detection of virus-specific antibodies. While in theory complementary, both PCR and serologic tests have practical shortcomings. A retrospective study was performed in order to further define these limitations in a clinical context and to determine how to best utilize these tests in a coherent fashion. A total of 3,075 patients underwent both PCR and serology tests at University of California, Los Angeles (UCLA), in the study period. Among these, 2,731 (89%) had no positive tests at all, 73 (2%) had a positive PCR test and only negative serology tests, 144 (5%) had a positive serology test and only negative PCR tests, and 127 (4%) had positive PCR and serology tests. Approximately half of the patients with discordant results (i.e., PCR positive and serology negative or vice versa) had mistimed tests in reference to the course of their disease. PCR-positive patients who were asymptomatic or pregnant were less likely to generate a detectable humoral immune response to SARS-CoV-2. On a quantitative level, the log number of days between symptom onset and PCR test was positively correlated with cycle threshold (C(T)) values. However, there was no apparent relationship between PCR C(T) and serologic (arbitrary units per milliliter) results. |*COVID-19[MESH] |*SARS-CoV-2[MESH] |Antibodies, Viral[MESH] |Humans[MESH] |Los Angeles[MESH] |Polymerase Chain Reaction[MESH] |Retrospective Studies[MESH]SARS-CoV-2 Infection Detection by PCR and Serologic Testing in Clinica(epmc).pdf DeepDyve Pubget Overpricing