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10.1111/jcpe.13471

http://scihub22266oqcxt.onion/10.1111/jcpe.13471
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33899251!8251434!33899251
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suck abstract from ncbi


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pmid33899251      J+Clin+Periodontol 2021 ; 48 (7): 880-885
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  • Dental biofilm of symptomatic COVID-19 patients harbours SARS-CoV-2 #MMPMID33899251
  • Gomes SC; Fachin S; da Fonseca JG; Angst PDM; Lamers ML; da Silva ISB; Nunes LN
  • J Clin Periodontol 2021[Jul]; 48 (7): 880-885 PMID33899251show ga
  • AIMS: SARS-CoV-2 RNA has been recovered from different sites in the human body, including the mouth. The present study aimed to investigate the presence of SARS-CoV-2 RNA in the dental biofilm of symptomatic patients who tested positive in nasopharyngeal and oropharyngeal (NASO/ORO) samples. MATERIALS & METHODS: An observational clinical study of individuals with flu-like symptoms was conducted between July and September 2020. Dental biofilm (BIO) samples were collected and analysed using real-time quantitative polymerase chain reaction (RT-qPCR) to determine the virus's presence. RESULTS: Seventy participants (40 +/- 9.8 years of age, 71.4% female) tested positive for SARS-CoV-2 RNA in NASO/ORO samples and were included in the study. Among them, 13 tested positive in BIO samples (18.6%; 95% CI: [9.5, 27.7]). The median and interquartile range of cycle quantification (Cq) for NASO/ORO and BIO samples were 15.9 [6.9] and 35.9 [4.0] (p = .001), respectively. BIO-positive participants showed a higher virus load in NASO/ORO samples (p = .012) than those testing negative (Cq = 20.4 [6.1]). CONCLUSIONS: Dental biofilms from symptomatic COVID-19 patients harbour SARS-CoV-2 RNA and might be a potential reservoir with an essential role in COVID-19 transmission.
  • |*COVID-19[MESH]
  • |*SARS-CoV-2[MESH]
  • |Aged[MESH]
  • |Biofilms[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |RNA, Viral[MESH]
  • |Real-Time Polymerase Chain Reaction[MESH]


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