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10.1016/j.xcrm.2021.100269

http://scihub22266oqcxt.onion/10.1016/j.xcrm.2021.100269
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33899032!8055165!33899032
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suck abstract from ncbi


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pmid33899032      Cell+Rep+Med 2021 ; 2 (5): 100269
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  • Soluble interleukin-6 receptor in the COVID-19 cytokine storm syndrome #MMPMID33899032
  • Chen LYC; Biggs CM; Jamal S; Stukas S; Wellington CL; Sekhon MS
  • Cell Rep Med 2021[May]; 2 (5): 100269 PMID33899032show ga
  • Data suggest that interleukin (IL)-6 blockade could reduce mortality in severe COVID-19, yet IL-6 is only modestly elevated in most patients. Chen et al. describe the role of soluble interleukin-6 receptor (sIL-6R) in IL-6 trans-signaling and how understanding the IL-6:sIL-6R axis might help define and treat COVID-19 cytokine storm syndrome.
  • |Antibodies, Monoclonal/immunology/pharmacology[MESH]
  • |COVID-19/complications/*pathology/virology[MESH]
  • |Cytokine Release Syndrome/*diagnosis/etiology[MESH]
  • |Humans[MESH]
  • |Interleukin-6/analysis/immunology[MESH]
  • |Receptors, Interleukin-6/*analysis[MESH]
  • |SARS-CoV-2/isolation & purification[MESH]


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