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10.1016/j.heliyon.2021.e06836

http://scihub22266oqcxt.onion/10.1016/j.heliyon.2021.e06836
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suck abstract from ncbi


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pmid33898857      Heliyon 2021 ; 7 (4): e06836
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  • Landscape of humoral immune responses against SARS-CoV-2 in patients with COVID-19 disease and the value of antibody testing #MMPMID33898857
  • Mahalingam S; Peter J; Xu Z; Bordoloi D; Ho M; Kalyanaraman VS; Srinivasan A; Muthumani K
  • Heliyon 2021[Apr]; 7 (4): e06836 PMID33898857show ga
  • A new pandemic is ongoing in several parts of the world. The agent responsible is the newly emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The symptoms associated with this virus are known as the coronavirus disease-2019 (COVID-19). In this review, we summarize the published data on virus specific antibodies in hospitalized patients with COVID-19 disease, patients recovered from the disease and the individuals who are asymptomatic with SARS-CoV-2 infections. The review highlights the following: i) an adjunct role of antibody tests in the diagnosis of COVID-19 in combination with RT-PCR; ii) status of antibodies from COVID-19 convalescent patients to select donors for plasma therapy; iii) the potential confounding effects of other coronaviruses, measles, mumps and rubella in antibody testing due to homology of certain viral genes; and iv) the role of antibody testing for conducting surveillance in populations, incidence estimation, contact tracing and epidemiologic studies.
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