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10.1016/j.biopha.2021.111626

http://scihub22266oqcxt.onion/10.1016/j.biopha.2021.111626
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suck abstract from ncbi


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pmid33894625      Biomed+Pharmacother 2021 ; 139 (ä): 111626
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  • Resveratrol-zinc nanoparticles or pterostilbene-zinc: Potential COVID-19 mono and adjuvant therapy #MMPMID33894625
  • Kelleni MT
  • Biomed Pharmacother 2021[Jul]; 139 (ä): 111626 PMID33894625show ga
  • In this manuscript we provide the scientific basis to adopt a novel combination of two widely available nutraceuticals; resveratrol and zinc in management of COVID-19 recommending their administration using a nano-carrier based drug-delivery system. Resveratrol, a well-known antioxidant and anti-inflammatory triphenolic stilbene, is abundant in red grapes, red wine, dark chocolate, and peanut butter. Alternatively, pterostilbene-zinc combination might be also considered without using a nano-carrier. We recommend conducting prompt clinical trials to assess the potential of the suggested combinations as a monotherapy for mild COVID-19 with a potential to prevent its progression to moderate-severe disease for which we recommend their trial as an adjuvant therapy. Furthermore, the suggested combinations might also possess a pharmacotherapeutic potential that exceeds COVID-19 to various inflammatory, immunologic, and oncologic diseases.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Drug Delivery Systems[MESH]
  • |*Nanoparticles[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |Humans[MESH]
  • |Resveratrol/*therapeutic use[MESH]
  • |Stilbenes/*therapeutic use[MESH]


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