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10.1016/j.ijid.2021.04.050

http://scihub22266oqcxt.onion/10.1016/j.ijid.2021.04.050
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suck abstract from ncbi


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pmid33892191      Int+J+Infect+Dis 2021 ; 107 (ä): 153-163
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  • Serum Calcium and Vitamin D levels: Correlation with severity of COVID-19 in hospitalized patients in Royal Hospital, Oman #MMPMID33892191
  • Osman W; Al Fahdi F; Al Salmi I; Al Khalili H; Gokhale A; Khamis F
  • Int J Infect Dis 2021[Jun]; 107 (ä): 153-163 PMID33892191show ga
  • INTRODUCTION: Studies have revealed hypocalcemia and low vitamin D levels in severe covid-19 that warrant further research. OBJECTIVE: Our study investigates the correlation between calcium levels at presentation as a primary endpoint and pre-existing calcium levels as a secondary endpoint to the severity of disease presentation and progression. METHOD: Observational cohort study in adults admitted with COVID-19 from March utill September 2020. Multiple clinical scales and laboratory parameters were used to correlate corrected calcium and vitamin D associations with risk factors and outcomes. RESULTS: Four hundred and forty five patients were included in the study. Hypocalcemic patients had more abnormal laboratory parameters and longer hospitalization duration. Hypocalcemia was in 60-75% of all age groups (p-value 0.053), for which 77.97% were ICU admissions (p-value 0.001) and 67.02% were diabetic (p-value 0.347). There were non-significant correlations between Vitamin D and almost all the parameters except for chronic respiratory diseases, which had a P-value of 0.024. CONCLUSION: It can be concluded that hypocalcemia is a significant and reliable marker of disease severity and progression regardless of underlying comorbidities. Vitamin D levels fail to reflect correlation with severity of COVID-19 infections.
  • |*SARS-CoV-2[MESH]
  • |*Severity of Illness Index[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*blood/complications[MESH]
  • |Calcium/*blood[MESH]
  • |Cohort Studies[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Hypocalcemia/blood[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Vitamin D/blood[MESH]


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