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10.1038/s41598-021-87254-3 http://scihub22266oqcxt.onion/10.1038/s41598-021-87254-3 33888738!8062499!33888738     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2021 ; 11 (1): 8692 Nephropedia Template TP {{tp|p=33888738|t=2021. Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses |pdf=|usr=}}{{33888738}} gab.com Text Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33888738 #FOAvip A metal nanoparticle composite, namely TPNT1, which contains Au-NP (1 ppm), Ag-NP (5 ppm), ZnO-NP (60 ppm) and ClO(2) (42.5 ppm) in aqueous solution was prepared and characterized by spectroscopy, transmission electron microscopy, dynamic light scattering analysis and potentiometric titration. Based on the in vitro cell-based assay, TPNT1 inhibited six major clades of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with effective concentration within the range to be used as food additives. TPNT1 was shown to block viral entry by inhibiting the binding of SARS-CoV-2 spike proteins to the angiotensin-converting enzyme 2 (ACE2) receptor and to interfere with the syncytium formation. In addition, TPNT1 also effectively reduced the cytopathic effects induced by human (H1N1) and avian (H5N1) influenza viruses, including the wild-type and oseltamivir-resistant virus isolates. Together with previously demonstrated efficacy as antimicrobials, TPNT1 can block viral entry and inhibit or prevent viral infection to provide prophylactic effects against both SARS-CoV-2 and opportunistic infections. Twit Text FOAVip Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33888738 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33888738 #FOAvip English Wikipedia <ref>{{Cite pmid|33888738}}</ref> Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses #MMPMID33888738 Chang SY; Huang KY; Chao TL; Kao HC; Pang YH; Lu L; Chiu CL; Huang HC; Cheng TR; Fang JM; Yang PC Sci Rep 2021[Apr]; 11 (1): 8692 PMID33888738show ga A metal nanoparticle composite, namely TPNT1, which contains Au-NP (1 ppm), Ag-NP (5 ppm), ZnO-NP (60 ppm) and ClO(2) (42.5 ppm) in aqueous solution was prepared and characterized by spectroscopy, transmission electron microscopy, dynamic light scattering analysis and potentiometric titration. Based on the in vitro cell-based assay, TPNT1 inhibited six major clades of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with effective concentration within the range to be used as food additives. TPNT1 was shown to block viral entry by inhibiting the binding of SARS-CoV-2 spike proteins to the angiotensin-converting enzyme 2 (ACE2) receptor and to interfere with the syncytium formation. In addition, TPNT1 also effectively reduced the cytopathic effects induced by human (H1N1) and avian (H5N1) influenza viruses, including the wild-type and oseltamivir-resistant virus isolates. Together with previously demonstrated efficacy as antimicrobials, TPNT1 can block viral entry and inhibit or prevent viral infection to provide prophylactic effects against both SARS-CoV-2 and opportunistic infections. |Angiotensin-Converting Enzyme 2/metabolism[MESH] |Antiviral Agents/chemistry/pharmacology[MESH] |Drug Resistance, Viral/drug effects[MESH] |Food Additives/pharmacology[MESH] |Gold/chemistry/*pharmacology[MESH] |HEK293 Cells[MESH] |Humans[MESH] |Influenza A Virus, H1N1 Subtype/drug effects/*physiology[MESH] |Influenza A Virus, H5N1 Subtype/drug effects/*physiology[MESH] |Metal Nanoparticles/chemistry[MESH] |Nanocomposites/chemistry[MESH] |Oseltamivir/pharmacology[MESH] |Particle Size[MESH] |Protein Binding/drug effects[MESH] |SARS-CoV-2/drug effects/*physiology[MESH] |Silver/chemistry/*pharmacology[MESH] |Spike Glycoprotein, Coronavirus/metabolism[MESH] |Virus Internalization/drug effects[MESH]Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influ(epmc).pdf DeepDyve Pubget Overpricing