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10.1016/j.tranon.2021.101095

http://scihub22266oqcxt.onion/10.1016/j.tranon.2021.101095
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suck abstract from ncbi


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pmid33887552      Transl+Oncol 2021 ; 14 (7): 101095
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  • Exploring the utility of extracellular vesicles in ameliorating viral infection-associated inflammation, cytokine storm and tissue damage #MMPMID33887552
  • Pillalamarri N; Abdullah; Ren G; Khan L; Ullah A; Jonnakuti S; Ullah M
  • Transl Oncol 2021[Jul]; 14 (7): 101095 PMID33887552show ga
  • Extracellular vesicles (EVs) have emerged as potential mediators of intercellular communication. EVs are nano-sized, lipid membrane-bound vesicles that contains biological information in the form of proteins, metabolites and/or nucleic acids. EVs are key regulators of tissue repair mechanisms, such as in the context of lung injuries. Recent studies suggest that EVs have the ability to repair COVID19-associated acute lung damage. EVs hold great promise for therapeutic treatments, particularly in treating a potentially fatal autoimmune response and attenuate inflammation. They are known to boost lung immunity and are involved in the pathogenesis of various lung diseases, including viral infection. EV-based immunization technology has been proven to elicit robust immune responses in many models of infectious disease, including COVID-19. The field of EV research has tremendous potential in advancing our understanding about viral infection pathogenesis, and can be translated into anti-viral therapeutic strategies.
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