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10.1056/NEJMoa2105000 http://scihub22266oqcxt.onion/10.1056/NEJMoa2105000 33882219!8117968!33882219     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       N+Engl+J+Med 2021 ; 384 (23): 2212-2218 Nephropedia Template TP {{tp|p=33882219|t=2021. Vaccine Breakthrough Infections with SARS-CoV-2 Variants |pdf=|usr=}}{{33882219}} gab.com Text Vaccine Breakthrough Infections with SARS-CoV-2 Variants JO: N Engl J Med http://www.kidney.de/pget.php?&tw=1&pmid=33882219 #FOAvip Emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of clinical concern. In a cohort of 417 persons who had received the second dose of BNT162b2 (Pfizer-BioNTech) or mRNA-1273 (Moderna) vaccine at least 2 weeks previously, we identified 2 women with vaccine breakthrough infection. Despite evidence of vaccine efficacy in both women, symptoms of coronavirus disease 2019 developed, and they tested positive for SARS-CoV-2 by polymerase-chain-reaction testing. Viral sequencing revealed variants of likely clinical importance, including E484K in 1 woman and three mutations (T95I, del142-144, and D614G) in both. These observations indicate a potential risk of illness after successful vaccination and subsequent infection with variant virus, and they provide support for continued efforts to prevent and diagnose infection and to characterize variants in vaccinated persons. (Funded by the National Institutes of Health and others.). Twit Text FOAVip Vaccine Breakthrough Infections with SARS-CoV-2 Variants ????N Engl J Med http://www.kidney.de/pget.php?&tw=1&pmid=33882219 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33882219 #FOAvip English Wikipedia <ref>{{Cite pmid|33882219}}</ref> Vaccine Breakthrough Infections with SARS-CoV-2 Variants #MMPMID33882219 Hacisuleyman E; Hale C; Saito Y; Blachere NE; Bergh M; Conlon EG; Schaefer-Babajew DJ; DaSilva J; Muecksch F; Gaebler C; Lifton R; Nussenzweig MC; Hatziioannou T; Bieniasz PD; Darnell RB N Engl J Med 2021[Jun]; 384 (23): 2212-2218 PMID33882219show ga Emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of clinical concern. In a cohort of 417 persons who had received the second dose of BNT162b2 (Pfizer-BioNTech) or mRNA-1273 (Moderna) vaccine at least 2 weeks previously, we identified 2 women with vaccine breakthrough infection. Despite evidence of vaccine efficacy in both women, symptoms of coronavirus disease 2019 developed, and they tested positive for SARS-CoV-2 by polymerase-chain-reaction testing. Viral sequencing revealed variants of likely clinical importance, including E484K in 1 woman and three mutations (T95I, del142-144, and D614G) in both. These observations indicate a potential risk of illness after successful vaccination and subsequent infection with variant virus, and they provide support for continued efforts to prevent and diagnose infection and to characterize variants in vaccinated persons. (Funded by the National Institutes of Health and others.). |*COVID-19 Vaccines[MESH] |*Mutation[MESH] |2019-nCoV Vaccine mRNA-1273[MESH] |Aged[MESH] |Antibodies, Neutralizing/*blood[MESH] |Antibodies, Viral/blood[MESH] |BNT162 Vaccine[MESH] |COVID-19/diagnosis/*virology[MESH] |Female[MESH] |Humans[MESH] |Middle Aged[MESH] |Neutralization Tests[MESH] |Phylogeny[MESH] |Polymerase Chain Reaction[MESH] |SARS-CoV-2/*genetics/immunology/isolation & purification[MESH] |Sequence Analysis, RNA[MESH] |Spike Glycoprotein, Coronavirus/genetics[MESH]Vaccine Breakthrough Infections with SARS-CoV-2 Variants (epmc).pdf DeepDyve Pubget Overpricing