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10.1161/STROKEAHA.120.032150 http://scihub22266oqcxt.onion/10.1161/STROKEAHA.120.032150 33878893!8240491!33878893     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Stroke 2021 ; 52 (7): 2422-2426 Nephropedia Template TP {{tp|p=33878893|t=2021. Transcranial Doppler in Acute COVID-19 Infection: Unexpected Associations |pdf=|usr=}}{{33878893}} gab.com Text Transcranial Doppler in Acute COVID-19 Infection: Unexpected Associations JO: Stroke http://www.kidney.de/pget.php?&tw=1&pmid=33878893 #FOAvip BACKGROUND AND PURPOSE: Stroke may complicate coronavirus disease 2019 (COVID-19) infection based on clinical hypercoagulability. We investigated whether transcranial Doppler ultrasound has utility for identifying microemboli and clinically relevant cerebral blood flow velocities (CBFVs) in COVID-19. METHODS: We performed transcranial Doppler for a consecutive series of patients with confirmed or suspected COVID-19 infection admitted to 2 intensive care units at a large academic center including evaluation for microembolic signals. Variables specific to hypercoagulability and blood flow including transthoracic echocardiography were analyzed as a part of routine care. RESULTS: Twenty-six patients were included in this analysis, 16 with confirmed COVID-19 infection. Of those, 2 had acute ischemic stroke secondary to large vessel occlusion. Ten non-COVID stroke patients were included for comparison. Two COVID-negative patients had severe acute respiratory distress syndrome and stroke due to large vessel occlusion. In patients with COVID-19, relatively low CBFVs were observed diffusely at median hospital day 4 (interquartile range, 3-9) despite low hematocrit (29.5% [25.7%-31.6%]); CBFVs in comparable COVID-negative stroke patients were significantly higher compared with COVID-positive stroke patients. Microembolic signals were not detected in any patient. Median left ventricular ejection fraction was 60% (interquartile range, 60%-65%). CBFVs were correlated with arterial oxygen content, and C-reactive protein (Spearman rho=0.28 [P=0.04]; 0.58 [P<0.001], respectively) but not with left ventricular ejection fraction (rho=-0.18; P=0.42). CONCLUSIONS: In this cohort of critically ill patients with COVID-19 infection, we observed lower than expected CBFVs in setting of low arterial oxygen content and low hematocrit but not associated with suppression of cardiac output. Twit Text FOAVip Transcranial Doppler in Acute COVID-19 Infection: Unexpected Associations ????Stroke http://www.kidney.de/pget.php?&tw=1&pmid=33878893 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33878893 #FOAvip English Wikipedia <ref>{{Cite pmid|33878893}}</ref> Transcranial Doppler in Acute COVID-19 Infection: Unexpected Associations #MMPMID33878893 Ziai WC; Cho SM; Johansen MC; Ergin B; Bahouth MN Stroke 2021[Jul]; 52 (7): 2422-2426 PMID33878893show ga BACKGROUND AND PURPOSE: Stroke may complicate coronavirus disease 2019 (COVID-19) infection based on clinical hypercoagulability. We investigated whether transcranial Doppler ultrasound has utility for identifying microemboli and clinically relevant cerebral blood flow velocities (CBFVs) in COVID-19. METHODS: We performed transcranial Doppler for a consecutive series of patients with confirmed or suspected COVID-19 infection admitted to 2 intensive care units at a large academic center including evaluation for microembolic signals. Variables specific to hypercoagulability and blood flow including transthoracic echocardiography were analyzed as a part of routine care. RESULTS: Twenty-six patients were included in this analysis, 16 with confirmed COVID-19 infection. Of those, 2 had acute ischemic stroke secondary to large vessel occlusion. Ten non-COVID stroke patients were included for comparison. Two COVID-negative patients had severe acute respiratory distress syndrome and stroke due to large vessel occlusion. In patients with COVID-19, relatively low CBFVs were observed diffusely at median hospital day 4 (interquartile range, 3-9) despite low hematocrit (29.5% [25.7%-31.6%]); CBFVs in comparable COVID-negative stroke patients were significantly higher compared with COVID-positive stroke patients. Microembolic signals were not detected in any patient. Median left ventricular ejection fraction was 60% (interquartile range, 60%-65%). CBFVs were correlated with arterial oxygen content, and C-reactive protein (Spearman rho=0.28 [P=0.04]; 0.58 [P<0.001], respectively) but not with left ventricular ejection fraction (rho=-0.18; P=0.42). CONCLUSIONS: In this cohort of critically ill patients with COVID-19 infection, we observed lower than expected CBFVs in setting of low arterial oxygen content and low hematocrit but not associated with suppression of cardiac output. |*Blood Flow Velocity[MESH] |*Cerebrovascular Circulation[MESH] |Adult[MESH] |Aged[MESH] |Blood Gas Analysis[MESH] |Brain/blood supply/*diagnostic imaging[MESH] |C-Reactive Protein/metabolism[MESH] |COVID-19/*diagnostic imaging/physiopathology[MESH] |Case-Control Studies[MESH] |Critical Illness[MESH] |Female[MESH] |Humans[MESH] |Ischemic Stroke/*diagnostic imaging/physiopathology[MESH] |Male[MESH] |Middle Aged[MESH] |Oxygen/blood[MESH] |Respiratory Distress Syndrome/diagnostic imaging/physiopathology[MESH] |SARS-CoV-2[MESH] |Stroke Volume/physiology[MESH]Transcranial Doppler in Acute COVID-19 Infection: Unexpected Associati(epmc).pdf DeepDyve Pubget Overpricing