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10.1701/3584.35698 http://scihub22266oqcxt.onion/10.1701/3584.35698 33877100!ä!33877100 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Recenti+Prog+Med 2021 ; 112 (4): 49e-52e Nephropedia Template TP {{tp|p=33877100|t=2021. Efficacia a lungo termine del trattamento di combinazione con encorafenib e binimetinib: caso clinico |pdf=|usr=}}{{33877100}} gab.com Text Efficacia a lungo termine del trattamento di combinazione con encorafenib e binimetinib: caso clinico JO: Recenti Prog Med http://www.kidney.de/pget.php?&tw=1&pmid=33877100 #FOAvip Combination treatment with BRAF plus MEK inhibitors is a standard of care in patients with BRAF-mutant advanced melanoma. In addition to dabrafenib+trametinib and vemurafenib+cobimetinib, a new combination of BRAF and MEK inhibitors, encorafenib and binimetinib, was recently introduced into clinical practice. Encorafenib plus binimetinib achieved similar efficacy to that observed with previously available combinations, but incidence of some toxicities such as pyrexia and photosensitivity, which have a relevant impact on patients quality of life, is lower. In this article, the case of a patient who received encorafenib and binimetinib within the phase 3 trial COLUMBUS is presented and discussed, with a focus on the clinical management during the pandemic caused by SARS-CoV-2 virus. Twit Text FOAVip Efficacia a lungo termine del trattamento di combinazione con encorafenib e binimetinib: caso clinico ????Recenti Prog Med http://www.kidney.de/pget.php?&tw=1&pmid=33877100 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33877100 #FOAvip English Wikipedia <ref>{{Cite pmid|33877100}}</ref> Efficacia a lungo termine del trattamento di combinazione con encorafenib e binimetinib: caso clinico #MMPMID33877100 Spagnolo F Recenti Prog Med 2021[Apr]; 112 (4): 49e-52e PMID33877100show ga Combination treatment with BRAF plus MEK inhibitors is a standard of care in patients with BRAF-mutant advanced melanoma. In addition to dabrafenib+trametinib and vemurafenib+cobimetinib, a new combination of BRAF and MEK inhibitors, encorafenib and binimetinib, was recently introduced into clinical practice. Encorafenib plus binimetinib achieved similar efficacy to that observed with previously available combinations, but incidence of some toxicities such as pyrexia and photosensitivity, which have a relevant impact on patients quality of life, is lower. In this article, the case of a patient who received encorafenib and binimetinib within the phase 3 trial COLUMBUS is presented and discussed, with a focus on the clinical management during the pandemic caused by SARS-CoV-2 virus. |Aged[MESH] |Benzimidazoles/*administration & dosage[MESH] |COVID-19[MESH] |Carbamates/*administration & dosage[MESH] |Drug Combinations[MESH] |Female[MESH] |Humans[MESH] |Melanoma/*drug therapy[MESH] |Skin Neoplasms/*drug therapy[MESH] |Sulfonamides/*administration & dosage[MESH] |Time Factors[MESH]Efficacia a lungo termine del trattamento di combinazione con encorafe(epmc).pdf DeepDyve Pubget Overpricing