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10.1016/j.tips.2021.03.006

http://scihub22266oqcxt.onion/10.1016/j.tips.2021.03.006
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33867130!7997307!33867130
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suck abstract from ncbi


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pmid33867130      Trends+Pharmacol+Sci 2021 ; 42 (6): 431-433
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  • Therapeutic Potential of Targeting Plasminogen Activator Inhibitor-1 in COVID-19 #MMPMID33867130
  • Kellici TF; Pilka ES; Bodkin MJ
  • Trends Pharmacol Sci 2021[Jun]; 42 (6): 431-433 PMID33867130show ga
  • Latest research shows that SERPINE1 overexpression has an important role in Coronavirus 2019 (COVID-19)-associated coagulopathy leading to acute respiratory distress syndrome (ARDS). However, ways to target this protein remain elusive. In this forum, we discuss recent evidence linking SERPINE1 with COVID-19-related ARDS and summarize the available data on inhibitors of this target.
  • |*COVID-19[MESH]
  • |*Respiratory Distress Syndrome[MESH]
  • |Complement Activation[MESH]
  • |Humans[MESH]


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