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10.1093/bib/bbab110 http://scihub22266oqcxt.onion/10.1093/bib/bbab110 33866350!8083275!33866350     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33866350&cmd=llinks): Failed to open stream: HTTP request failed! 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Is acupuncture effective in the treatment of COVID-19 related symptoms? Based on bioinformatics/network topology strategy |pdf=|usr=}}{{33866350}} gab.com Text Is acupuncture effective in the treatment of COVID-19 related symptoms Based on bioinformatics/network topology strategy JO: Brief Bioinform http://www.kidney.de/pget.php?&tw=1&pmid=33866350 #FOAvip Acupuncture is an important part of Chinese medicine that has been widely used in the treatment of inflammatory diseases. During the coronavirus disease 2019 (COVID-19) epidemic, acupuncture has been used as a complementary treatment for COVID-19 in China. However, the underlying mechanism of acupuncture treatment of COVID-19 remains unclear. Based on bioinformatics/topology, this paper systematically revealed the multi-target mechanisms of acupuncture therapy for COVID-19 through text mining, bioinformatics, network topology, etc. Two active compounds produced after acupuncture and 180 protein targets were identified. A total of 522 Gene Ontology terms related to acupuncture for COVID-19 were identified, and 61 pathways were screened based on the Kyoto Encyclopedia of Genes and Genomes. Our findings suggested that acupuncture treatment of COVID-19 was associated with suppression of inflammatory stress, improving immunity and regulating nervous system function, including activation of neuroactive ligand-receptor interaction, calcium signaling pathway, cancer pathway, viral carcinogenesis, Staphylococcus aureus infection, etc. The study also found that acupuncture may have additional benefits for COVID-19 patients with cancer, cardiovascular disease and obesity. Our study revealed for the first time the multiple synergistic mechanisms of acupuncture on COVID-19. Acupuncture may play an active role in the treatment of COVID-19 and deserves further promotion and application. These results may help to solve this pressing problem currently facing the world. Twit Text FOAVip Is acupuncture effective in the treatment of COVID-19 related symptoms Based on bioinformatics/network topology strategy ????Brief Bioinform http://www.kidney.de/pget.php?&tw=1&pmid=33866350 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33866350 #FOAvip English Wikipedia <ref>{{Cite pmid|33866350}}</ref> Is acupuncture effective in the treatment of COVID-19 related symptoms? Based on bioinformatics/network topology strategy #MMPMID33866350 Han Z; Zhang Y; Wang P; Tang Q; Zhang K Brief Bioinform 2021[Sep]; 22 (5): ä PMID33866350show ga Acupuncture is an important part of Chinese medicine that has been widely used in the treatment of inflammatory diseases. During the coronavirus disease 2019 (COVID-19) epidemic, acupuncture has been used as a complementary treatment for COVID-19 in China. However, the underlying mechanism of acupuncture treatment of COVID-19 remains unclear. Based on bioinformatics/topology, this paper systematically revealed the multi-target mechanisms of acupuncture therapy for COVID-19 through text mining, bioinformatics, network topology, etc. Two active compounds produced after acupuncture and 180 protein targets were identified. A total of 522 Gene Ontology terms related to acupuncture for COVID-19 were identified, and 61 pathways were screened based on the Kyoto Encyclopedia of Genes and Genomes. Our findings suggested that acupuncture treatment of COVID-19 was associated with suppression of inflammatory stress, improving immunity and regulating nervous system function, including activation of neuroactive ligand-receptor interaction, calcium signaling pathway, cancer pathway, viral carcinogenesis, Staphylococcus aureus infection, etc. The study also found that acupuncture may have additional benefits for COVID-19 patients with cancer, cardiovascular disease and obesity. Our study revealed for the first time the multiple synergistic mechanisms of acupuncture on COVID-19. Acupuncture may play an active role in the treatment of COVID-19 and deserves further promotion and application. These results may help to solve this pressing problem currently facing the world. |*Acupuncture[MESH] |COVID-19/physiopathology/*therapy/virology[MESH] |Computational Biology/*methods[MESH] |Humans[MESH] |SARS-CoV-2/isolation & purification[MESH]Is acupuncture effective in the treatment of COVID-19 related symptoms(epmc).pdf DeepDyve Pubget Overpricing