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10.1542/peds.2021-050182 http://scihub22266oqcxt.onion/10.1542/peds.2021-050182 33863845!8276592!33863845     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33863845&cmd=llinks): Failed to open stream: HTTP request failed! 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SARS-CoV-2 Infection Dynamics in Children and Household Contacts in a Slum in Rio de Janeiro |pdf=|usr=}}{{33863845}} gab.com Text SARS-CoV-2 Infection Dynamics in Children and Household Contacts in a Slum in Rio de Janeiro JO: Pediatrics http://www.kidney.de/pget.php?&tw=1&pmid=33863845 #FOAvip OBJECTIVES: To investigate the dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in a vulnerable population of children and their household contacts. METHODS: SARS-CoV-2 reverse transcription polymerase chain reaction assays and coronavirus disease 2019 (COVID-19) immunoglobulin G serology tests were performed in children and their household contacts after enrollment during primary health care clinic visits. Participants were followed prospectively with subsequent specimens collected through household visits in Manguinhos, an impoverished urban slum (a favela) in Rio de Janeiro at 1, 2, and 4 weeks and quarterly post study enrollment. RESULTS: Six hundred sixty-seven participants from 259 households were enrolled from May to September 2020. This included 323 children (0-13 years), 54 adolescents (14-19 years), and 290 adults. Forty-five (13.9%) children had positive test results for SARS-CoV-2 polymerase chain reaction. SARS-CoV-2 infection was most frequent in children aged <1 year (25%) and children aged 11 to 13 years (21%). No child had severe COVID-19 symptoms. Asymptomatic infection was more prevalent in children aged <14 years than in those aged >/=14 years (74.3% and 51.1%, respectively). All children (n = 45) diagnosed with SARS-CoV-2 infection had an adult contact with evidence of recent infection. CONCLUSIONS: In our setting, children do not seem to be the source of SARS-CoV-2 infection and most frequently acquire the virus from adults. Our findings suggest that, in settings such as ours, schools and child care potentially may be reopened safely if adequate COVID-19 mitigation measures are in place and staff are appropriately immunized. Twit Text FOAVip SARS-CoV-2 Infection Dynamics in Children and Household Contacts in a Slum in Rio de Janeiro ????Pediatrics http://www.kidney.de/pget.php?&tw=1&pmid=33863845 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33863845 #FOAvip English Wikipedia <ref>{{Cite pmid|33863845}}</ref> SARS-CoV-2 Infection Dynamics in Children and Household Contacts in a Slum in Rio de Janeiro #MMPMID33863845 Lugon P; Fuller T; Damasceno L; Calvet G; Resende PC; Matos AR; Machado Fumian T; Malta FC; Salgado AD; Fernandes FCM; Abreu de Carvalho LM; Guaraldo L; Bastos L; Cruz OG; Whitworth J; Smith C; Nielsen-Saines K; Siqueira M; Carvalho MS; Brasil P Pediatrics 2021[Jul]; 148 (1): ä PMID33863845show ga OBJECTIVES: To investigate the dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in a vulnerable population of children and their household contacts. METHODS: SARS-CoV-2 reverse transcription polymerase chain reaction assays and coronavirus disease 2019 (COVID-19) immunoglobulin G serology tests were performed in children and their household contacts after enrollment during primary health care clinic visits. Participants were followed prospectively with subsequent specimens collected through household visits in Manguinhos, an impoverished urban slum (a favela) in Rio de Janeiro at 1, 2, and 4 weeks and quarterly post study enrollment. RESULTS: Six hundred sixty-seven participants from 259 households were enrolled from May to September 2020. This included 323 children (0-13 years), 54 adolescents (14-19 years), and 290 adults. Forty-five (13.9%) children had positive test results for SARS-CoV-2 polymerase chain reaction. SARS-CoV-2 infection was most frequent in children aged <1 year (25%) and children aged 11 to 13 years (21%). No child had severe COVID-19 symptoms. Asymptomatic infection was more prevalent in children aged <14 years than in those aged >/=14 years (74.3% and 51.1%, respectively). All children (n = 45) diagnosed with SARS-CoV-2 infection had an adult contact with evidence of recent infection. CONCLUSIONS: In our setting, children do not seem to be the source of SARS-CoV-2 infection and most frequently acquire the virus from adults. Our findings suggest that, in settings such as ours, schools and child care potentially may be reopened safely if adequate COVID-19 mitigation measures are in place and staff are appropriately immunized. |*Poverty Areas[MESH] |Adolescent[MESH] |Adult[MESH] |Brazil/epidemiology[MESH] |COVID-19 Serological Testing[MESH] |COVID-19/diagnosis/epidemiology/*transmission[MESH] |Child[MESH] |Child, Preschool[MESH] |Family Characteristics[MESH] |Female[MESH] |Humans[MESH] |Infant[MESH] |Male[MESH] |Prospective Studies[MESH] |SARS-CoV-2/*physiology[MESH]SARS-CoV-2 Infection Dynamics in Children and Household Contacts in a (epmc).pdf DeepDyve Pubget Overpricing