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10.1155/2021/6615787 http://scihub22266oqcxt.onion/10.1155/2021/6615787 33854695!8019372!33854695     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oxid+Med+Cell+Longev 2021 ; 2021 (ä): 6615787 Nephropedia Template TP {{tp|p=33854695|t=2021. Predicting Severity and Intrahospital Mortality in COVID-19: The Place and Role of Oxidative Stress |pdf=|usr=}}{{33854695}} gab.com Text Predicting Severity and Intrahospital Mortality in COVID-19: The Place and Role of Oxidative Stress JO: Oxid Med Cell Longev http://www.kidney.de/pget.php?&tw=1&pmid=33854695 #FOAvip SARS-CoV-2 virus causes infection which led to a global pandemic in 2020 with the development of severe acute respiratory syndrome. Therefore, this study was aimed at examining its possible role in predicting severity and intrahospital mortality of COVID-19, alongside with other laboratory and biochemical procedures, clinical signs, symptoms, and comorbidity. This study, approved by the Ethical Committee of Clinical Center Kragujevac, was designed as an observational prospective cross-sectional clinical study which was conducted on 127 patients with diagnosed respiratory COVID-19 viral infection from April to August 2020. The primary goals were to determine the predictors of COVID-19 severity and to determine the predictors of the negative outcome of COVID-19 infection. All patients were divided into three categories: patients with a mild form, moderate form, and severe form of COVID-19 infection. All biochemical and laboratory procedures were done on the first day of the hospital admission. Respiratory (p < 0.001) and heart (p = 0.002) rates at admission were significantly higher in patients with a severe form of COVID-19. From all observed hematological and inflammatory markers, only white blood cell count (9.43 +/- 4.62, p = 0.001) and LDH (643.13 +/- 313.3, p = 0.002) were significantly higher in the severe COVID-19 group. We have observed that in the severe form of SARS-CoV-2, the levels of superoxide anion radicals were substantially higher than those in two other groups (11.3 +/- 5.66, p < 0.001) and the nitric oxide level was significantly lower in patients with the severe disease (2.66 +/- 0.45, p < 0.001). Using a linear regression model, TA, anosmia, ageusia, O(2) (-), and the duration at the ICU are estimated as predictors of severity of SARS-CoV-2 disease. The presence of dyspnea and a higher heart rate were confirmed as predictors of a negative, fatal outcome. Results from our study show that presence of hypertension, anosmia, and ageusia, as well as the duration of ICU stay, and serum levels of O(2) (-) are predictors of COVID-19 severity, while the presence of dyspnea and an increased heart rate on admission were predictors of COVID-19 mortality. Twit Text FOAVip Predicting Severity and Intrahospital Mortality in COVID-19: The Place and Role of Oxidative Stress ????Oxid Med Cell Longev http://www.kidney.de/pget.php?&tw=1&pmid=33854695 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33854695 #FOAvip English Wikipedia <ref>{{Cite pmid|33854695}}</ref> Predicting Severity and Intrahospital Mortality in COVID-19: The Place and Role of Oxidative Stress #MMPMID33854695 Cekerevac I; Turnic TN; Draginic N; Andjic M; Zivkovic V; Simovic S; Susa R; Novkovic L; Mijailovic Z; Andjelkovic M; Vukicevic V; Vulovic T; Jakovljevic V Oxid Med Cell Longev 2021[]; 2021 (ä): 6615787 PMID33854695show ga SARS-CoV-2 virus causes infection which led to a global pandemic in 2020 with the development of severe acute respiratory syndrome. Therefore, this study was aimed at examining its possible role in predicting severity and intrahospital mortality of COVID-19, alongside with other laboratory and biochemical procedures, clinical signs, symptoms, and comorbidity. This study, approved by the Ethical Committee of Clinical Center Kragujevac, was designed as an observational prospective cross-sectional clinical study which was conducted on 127 patients with diagnosed respiratory COVID-19 viral infection from April to August 2020. The primary goals were to determine the predictors of COVID-19 severity and to determine the predictors of the negative outcome of COVID-19 infection. All patients were divided into three categories: patients with a mild form, moderate form, and severe form of COVID-19 infection. All biochemical and laboratory procedures were done on the first day of the hospital admission. Respiratory (p < 0.001) and heart (p = 0.002) rates at admission were significantly higher in patients with a severe form of COVID-19. From all observed hematological and inflammatory markers, only white blood cell count (9.43 +/- 4.62, p = 0.001) and LDH (643.13 +/- 313.3, p = 0.002) were significantly higher in the severe COVID-19 group. We have observed that in the severe form of SARS-CoV-2, the levels of superoxide anion radicals were substantially higher than those in two other groups (11.3 +/- 5.66, p < 0.001) and the nitric oxide level was significantly lower in patients with the severe disease (2.66 +/- 0.45, p < 0.001). Using a linear regression model, TA, anosmia, ageusia, O(2) (-), and the duration at the ICU are estimated as predictors of severity of SARS-CoV-2 disease. The presence of dyspnea and a higher heart rate were confirmed as predictors of a negative, fatal outcome. Results from our study show that presence of hypertension, anosmia, and ageusia, as well as the duration of ICU stay, and serum levels of O(2) (-) are predictors of COVID-19 severity, while the presence of dyspnea and an increased heart rate on admission were predictors of COVID-19 mortality. |*Oxidative Stress[MESH] |Adult[MESH] |Aged[MESH] |Antioxidants/analysis[MESH] |Biomarkers/blood[MESH] |COVID-19/blood/diagnosis/*mortality/*pathology[MESH] |Cross-Sectional Studies[MESH] |Female[MESH] |Hospital Mortality[MESH] |Hospitalization[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Oxidants/blood[MESH] |Prognosis[MESH] |Prospective Studies[MESH] |SARS-CoV-2[MESH]Predicting Severity and Intrahospital Mortality in COVID-19: The Place(epmc).pdf DeepDyve Pubget Overpricing